Dokumente Fakultät für Physik (inkl. GAUSS) nach Gutachter "Enderlein, Jörg Prof. Dr."
Anzeige 21-34 von 34
-
Optogenetic Control of Cardiac Arrhythmias
(2022-01-04)The regular, coordinated contraction of the heart muscle is orchestrated by periodic waves generated by the heart’s natural pacemaker and transmitted through the heart’s electrical conduction system. Abnormalities occurring ... -
Prinzipien und Anwendungen der Strukturierung und Bildgebung durch optisches Schalten von Farbstoffen
(2018-01-26)In this work, a novel ablative technique for transparent materials, based on a combination of the STimulated Emission Depletion (STED) and Laser Induced Backside Wet Etching (LIBWE), is presented. This new technique uses ... -
Probing Lipid Diffusion in Curved and Planar Membranes with Fluorescence Microscopy
(2017-09-05)Diffusion is the most important transport mechanism in biological membranes and essential for processes such as signalling or trafficking. Many different techniques have given insight into this matter, most of which are ... -
Ratiometric fluorescence imaging and marker-free motion tracking of Langendorff perfused beating rabbit hearts
(2021-01-06)Optical mapping is a fluorescence based imaging technique used extensively in cardiac research to study the electrophysiological properties of isolated hearts kept at physiological conditions. The major limitation of ... -
Scanning X-Ray Nanodiffraction on Dictyostelium discoideum
(2015-11-06)In the recent years, novel focussing optics for synchrotron radiation sources became available, which now allow focussing the x-radiation down to 100\,nm (FWHM). Thus, the typically poor spatial resolution of Small Angle ... -
Single-molecule experiments with mitotic motor proteins
(2012-10-24)This cumulative PhD thesis covers in five chapters (chapters 2, 3, 4 and 5 consisting of published papers and chapter 6 consisting of a submitted manuscript) new findings on different aspects of the regulation of kinesin-5 ... -
Stereo 3D-SMS microscopy of large sample volume
(2018-12-20)The functionality of the human body and with it many of its diseases are based on single cells or even on single cellular components. It is therefore essential to gain insight into the intra- and intercellular processes ... -
The reconstitution of visual cortical feature selectivity <i>in vitro</i>
(2018-02-09)Information processing in the nervous system requires the co-ordinated activity of neurons interacting in complex circuits. Despite effort to understand the design principles underlying most neuronal circuits, they remain ... -
Time-resolved X-ray phase-contrast tomography
(2018-06-27)X-ray tomography allows to obtain the three-dimensional (3d) structure of weakly interacting objects, such as tissue samples in biomedical imaging or nanoscale structures in materials science, with high spatial resolution. ... -
Tomographic STED Microscopy
(2017-03-09)Due to its non-invasive access to sub-cellular structures, far-field fluorescence microscopy constitutes one of the most prevalent methods in the life sciences. For more than one century, it had been common knowledge ... -
Towards an active matter perspective on sarcomere dynamics in cardiomyocytes
(2023-04-19)The contraction of cardiac muscles emerges from the collective dynamics of myosin motor proteins organized in sarcomeres, 2 μm-sized contractile units. Inside individual cardiomyocytes, dozens of sarcomeres in series form ... -
Towards validation and map quality assessment in electron cryo-microscopy
(2020-09-10)Structural biology is the study of the assembly of proteins and protein complexes. These proteins and protein complexes are small units in the cell of a living being. In order to sustain life they take care of biochemical ... -
Transfer RNA translocation through the ribosome
(2015-02-24)During the elongation cycle, ribosomes create peptides from an mRNA blueprint. To prime the ribosome for a new round of elongation after peptide bond formation, the transfer RNA (tRNA) bound to the aminoacyl site (A site) ... -
Variational Approaches to Free Energy Calculations
(2021-01-21)Gradients in free energy are the driving forces of thermodynamic systems. Knowledge thereof thus enables a first-principles understanding of condensed-phase many-body systems such as macromolecular assemblies, colloids or ...