Browsing Fakultät für Physik (inkl. GAUSS) by Referee "Griesinger, Christian Prof. Dr."
Now showing items 1-12 of 12
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Correlated and Further Dynamics in Proteins by NMR Spectroscopy
(2011-09-27)In the first part of this thesis the use of three NMR parameter for the detection of protein dynamics are investigated. The knowledge about the dynamics of proteins is essential for the ... -
Crystalline, membrane-embedded, and fibrillar proteins investigated by solid-state NMR spectroscopy
(2009-08-10)This thesis describes research on atomic structure and molecular dynamics of biomolecules in the solid phase using solid-state nuclear magnetic resonance spectroscopy. A method for ... -
From Slow to Ultra-fast MAS: Structural Determination of Type-Three Secretion System Bacterial Needles and Inorganic Materials by Solid-State NMR
(2014-12-16)This work on solid-state NMR methodologies and applications is divided in three parts. In the first part, three methods for solid-state NMR at ultra-fast Magic-Angle Spinning (MAS) are introduced: completely low-power ... -
New Methods in NMR Spectroscopy for the Study of Protein Dynamics
(2009-01-21)The focus of this work has been the investigation of internal protein dynamics in a time window between the overall tumbling correlation time tau_c (a few nanoseconds) and about 50 microseconds ... -
Protein precipitates, aggregation kinetics and membrane protein receptors characterized by solid-state NMR
(2008-10-01)This work addresses the investigation of insoluble, biomolecular systems using nuclear magnetic resonance (NMR). Introducing novel areas of applications an atomic picture of the precipitated ... -
Rapid Determination of High-Resolution Protein Structures by Solution and Solid-state NMR Spectroscopy
(2008-04-08)NMR spectroscopy provides high-resolution structural information of biomolecules in near-physiological conditions. Structural studies of proteins and nucleic acids are critical for understanding biological processes at ... -
Rapid Determination of Protein Structures in Solution Using NMR Dipolar Couplings
(2005-04-06)Once NMR spectra are measured, two main steps follow to determine NMR structure. One is backbone resonance assignment and the other is structure calculation. The both are time consuming ... -
Sensitivity Enhancement of Liquid-State NMR and Improvement of the INPHARMA Method
(2011-03-07)In the presented work the possibility of signal enhancement of high-resolution nuclear-magnetic-resonance (NMR) in aqueous solution, with the intent of application to macromolecular ... -
Solid-state NMR of (membrane) protein complexes: Novel methods and applications
(2006-07-06)The aim of this thesis was to develop multidimensional high-resolution experiments that can be incorporated in a general strategy for 3D structure determination of uniformly labeled membrane ... -
Structural characterization of membrane proteins by solid-state NMR spectroscopy
(2008-07-25)In this work, nuclear magnetic resonance spectroscopy was employed to characterize the three-dimensional atomic structure of proteins and other biomolecules in the solid phase. A method for ... -
Three-dimensional protein structure determination by high-resolution solid-state NMR spectroscopy
(2006-06-13)In this thesis a general concept for three-dimensional (3D) structure determination of uniformly [13C, 15N] labeled proteins by solid-state NMR spectroscopy has been developed. It is based ... -
Understanding the molecular machinery of aquaporins through molecular dynamics simulations
(2012-01-02)Aquaporins are protein channels responsible for the permeation of water and other small solutes through biological membranes in response to osmotic pressure. The goal of the present thesis ...