Browsing Naturwissenschaften, Mathematik und Informatik by Advisor "Ackermann, Lutz Prof. Dr."
Now showing items 21-40 of 61
-
Iron-Catalyzed C–H/N–H Activations for Annulation of Allenes, Alkynes, and Bicyclopropylidenes
(2020-11-16)Iron-catalyzed C–H/N–H activations for the annulation of allenes, alkynes, and bicyclopropylidenes were realized by using a customizable clickable triazole amide under mild reaction conditions. The powerful iron catalysis ... -
Late-Stage Peptide Diversification via Transition Metal-Catalyzed C─H Activation
(2020-10-13)The late-stage modification of peptide is of great value to drug discovery and medicinal chemistry. Metal catalyzed C─H activation has emerged as efficient and step-economic strategy for post-translational peptide engineering. ... -
Site-Selectivity in Ruthenium-Catalyzed C–H and C–C Activations
(2020-09-23)During the past decades, transition metal-catalyzed C–H and C–C activation has been recognized as a powerful platform in organic synthesis to access the selective construction of new C–C and C–Het bonds. The full control ... -
Metallaelectro-Catalyzed C─H Activations by 3d Transition Metals
(2020-09-17)The functionalization of C–H bonds largely relies on organic (pseudo-)halide electrophiles as coupling partners, which results in stoichiometric quantities of undesired by-products. Therefore, to achieve better resource ... -
Sustainable Synthesis by 3d Transition Metal Electro-Catalyzed C─H Activation
(2020-01-20)During the last years, new opportunities are represented by the development of 3d transition metal-catalyzed C–H activation, with possible benefits due to the significantly lower toxicity, high natural abundance and ... -
Development of Photo-Induced C–H Activation by Copper and Ruthenium Catalysis
(2019-11-08)Within recent decades, transition metal-catalyzed C–H activation has become a valuable and versatile tool for organic synthesis. As C–H bonds are ubiquitous in organic molecules, the direct site-selective functionalization ... -
Experimental and Computational Studies on Ruthenium- and Manganese-Catalyzed C-H and C-C Activation
(2019-11-07)During the last years, transition metal-catalyzed C–H and C–C activation has emerged as a powerful tool for the selective construction of C–C and C–Het bonds. In this context, a detailed mechanistic understanding of these ... -
Selectivity Control in 3d Transition Metal-Catalyzed C–H Activation
(2019-08-23)Methods for the selective functionalization of otherwise inert C–H bonds have been recognized as a transformative tool in synthetic organic chemistry, with applications ranging from the synthesis of complex bioactive ... -
C-H Activation by Nickel and Iron Catalysis
(2019-08-08)The thesis contents methods for the selective activation and functionalization of C–H bonds, among the most abundant bonds in organic molecules. In particular, earth-abundant and cost-effective nickel and iron complexes ... -
Cobalt(III)- and Manganese(I)-Catalyzed C-H and C-C Activations
(2019-03-28)Metal-catalyzed C─H and C─C functionalizations have become an increasingly viable approach, which allows the direct formation of C─C and C─heteroatom bonds in an atom- and step-economical manner. However, the significant ... -
Ruthenium- and Cobalt-Catalyzed C-H Activation
(2018-11-12)The thesis contents methods for the ruthenium- and cobalt catalyzed C-H activation of arenes. Ruthenium(II) catalysis was used to alkenylate arylacetamides using acrylates or alkynes. Further, ruthenium-catalyzed C-H ... -
Late-Stage Peptide Functionalization by Ruthenium-Catalyzed C H Arylations and Alkylations
(2018-11-08)The thesis contents methods for the selective activation and functionalization of C–H bonds of the C2 position of a tryptophan moiety incorporated into peptides. Palladium-catalyzed C-H arylation reactions applying ... -
Aerobic Ruthenium-Catalyzed C–H Activations
(2018-08-31)Within the last decades C–H activation processes have evolved from a promising concept to a powerful class of reactions for the construction of organic molecules, especially pharmaceutically active compounds. Within this ... -
C-H Activation for Sustainable Synthesis: Base Metal- and Electro-Catalysis
(2018-08-07)In the recent decades, metal-catalyzed C-H activation greatly expanded the available tools for the sustainable synthesis of bioactive molecules and organic materials. Within this thesis, new synthetic transformations based ... -
C-H and C-C Activation by Cobalt and Ruthenium Catalysis
(2017-12-18)The thesis contents methods for the selective activation and functionalization of C–H and C–C bonds, among the most abundant bonds in organic molecules. In particular, earth-abundant and cost-effective cobalt complexes ... -
C−H Alkylations and Alkynylations Using Ruthenium, Nickel and Manganese Complexes
(2017-10-17)Transition metal-catalyzed C–H functionalizations have recently emerged as a reliable tool for the efficient chemo- and site-selective construction of C–C and C–Het bonds, which is of major importance for the preparation ... -
Ruthenium- and Cobalt-Catalyzed Chelation-Assisted C–H Functionalization
(2017-09-11)Catalytic C−H functionalization has emerged as an economically-attractive and environmentally-benign alternative to conventional cross-coupling approaches. Thus, major efforts have been made on transformations of inert C–H ... -
C–H Activation by Ruthenium(II), Cobalt(III) and Manganese(I) Catalysis
(2017-07-07)C–H functionalizations have expanded the toolbox of organic chemistry and found widespread applications in the synthesis of complex and bioactive molecules. Within this thesis, several new synthetic transformations by ... -
Ruthenium(II)-Catalyzed C-N, C-O and C-C Formations by C-H Activation
(2017-02-16)Ruthenium catalyzed C-N, C-O and C-C formation is achieved by C-H activation. access to primary aminoketones leds to synthetic synthons for different heterocycles. removable and reusability was shown first time in C-O bond ... -
Homogeneous and Heterogeneous Chelation-Assisted Ruthenium(II)-Catalyzed C–H Functionalizations
(2017-01-03)Ruthenium(II)-catalyzed direct C–H functionalizations have emerged as a powerful tool for organic chemists to construct C–C and C–Het bonds. In order to rationally improve the efficiency of these methods a mechanistic ...