Browsing Naturwissenschaften, Mathematik und Informatik by Advisor "Ficner, Ralf Prof. Dr."
Now showing items 21-24 of 24
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Elektronenmikroskopische 3D Strukturbestimmung des Spleißosoms
(2005-08-15)In order to elucidate the conformational changes of the spliceosome that occur during its catalytic activation it is necessary to obtain high resolution 3D structures. The 3D structure of ... -
Investigation of Protein-protein Interactions within the Human Spliceosomal U4/U6.U5 tri-snRNP Particle
(2005-08-08)Two-hybrid data allowed me to define the regions through which proteins 220K, 200K, and 116K interact with each other. These regions include the N terminal and C-terminal domains of protein ... -
Crystallographic studies on a cold adapted subtilase and proteins involved in mRNA processing
(2005-06-03)The crystal structure of a subtilisin-like serine proteinase from the psychrotrophic marine bacterium, Vibrio sp. PA-44, was solved by means of molecular replacement and refined at 1.84 Å ... -
Strukturelle und funktionelle Untersuchungen zum m3G-Cap-vermittelten Kernimport spleißosomaler U snRNPs durch Snurportin1
(2005-02-01)During snRNP biogenesis the snRNAs are exported into the cytoplasm, where the assembly with the common Sm proteins occurs and the 5´cap nucleotide is modified from an 7-methyl-guanosine ...