Browsing Naturwissenschaften, Mathematik und Informatik by Referee "Einsle, Oliver Prof. Dr."
Now showing items 21-27 of 27
-
Struktur-Funtionsbeziehung in den spleißosomalen Proteinen des U4/U6•U5 tri-snRNP
(2007-01-29)Subject of this thesis is the splicesosmal U5-particle. The functional relationship of the proteins is investigated by means of limited proteolysis and spectroscopy. Due to the splicesosome's ... -
Kristallstrukturen der Aldose-Reduktase und der C2A-Domäne von Rabphilin3A sowie Überprüfungen neuer Restraints.
(2006-11-06)The high resolution (0.82 Å) structure of Aldose Reductase (an enzyme implicated in the polyol pathway) is presented. The aim of the work was a careful inspection of the model with particular ... -
Kristallstrukturen der C2B-Domäne von Rabphilin-3A und der PP2C-ähnlichen Phosphatase tPphA von Thermosynechococcus elongatus BP-1
(2006-09-28)The first part of this thesis deals with the x-ray crystal structure of the C2B domain of Rabphilin-3A, which includes part of the linker region between the C2A and C2B domain. The second ... -
Crystal structure of a human U5 snRNP specific binary complex and crystal structure of a histone deacetylase-like bacterial amidohydrolase
(2005-12-09)The crystal structure of the complex comprising the GYF-domain of U5-52K and the U5-15K protein has been determined at 2.35 Å resolution. The protein U5-52K (Lin1p) is a component of yeast ... -
Neue Enzyminhibitoren und Rezeptoragonisten durch Variation funktionaler Schleifen von Mikroproteinen
(2005-10-25)Cystine knot microproteins are peptidic biomolecules with approximately 28-40 amino acids in length. They are able to fold into extremely stable threedimensional structures characterized ... -
Präparation und röntgenkristallographische Untersuchungen an archaebakteriellen Box C/D sRNPs und einer neuartigen Glukosyltransferase aus Thermotoga maritima MSB8
(2005-10-18)A variety of posttranscriptional nucleotide modifications in ribosomal ribonucleic acids (RNAs) are directed by nucleolar RNAs (snoRNAs). The two major classes involved in these modifications ... -
Crystallographic studies on a cold adapted subtilase and proteins involved in mRNA processing
(2005-06-03)The crystal structure of a subtilisin-like serine proteinase from the psychrotrophic marine bacterium, Vibrio sp. PA-44, was solved by means of molecular replacement and refined at 1.84 Å ...