Browsing Naturwissenschaften, Mathematik und Informatik by Advisor "Laatsch, Hartmut Prof. Dr."
Now showing items 1-16 of 16
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Isolation, Purification and Structure Elucidation of New Secondary Metabolites from Terrestrial, Marine, and Ruminal Microorganisms
(2012-12-19)The search for microorganisms useful in agriculture, agroalimentary and pharmaceu-tical industries requires the exploration also of ecological niches. Thus, within this background, the rumen (one of the four stomach parts ... -
Bandamycin as New Antifungal Agent and further Secondary Metabolites from Terrestrial and Marine Microorganisms
(2012-05-03)In this study, eight terrestrial and two marine bacteria, and four endophytic fungi have been investigated chemically and pharmacologically, out of which a total of fourty-eight secondary metabolites were isolated. ... -
Indole Alkaloids as Potential Leads in Drug Discovery and Further Secondary Metabolites from Terrestrial and Marine Bacteria
(2012-01-04)Microorganisms take a large influence on ecological and symbiotic interactions in long-term relationships that are moderated by secondary metabolites with often-unique structure and biological ... -
Dehydrorabelomycin-1-O-α-L-rhamnopyranoside, Actinofuranone C and Further New Bioactive Secondary Metabolites from Terrestrial Streptomyces spp.
(2011-09-22)Natural products have been used to combat infectious diseases since ages. However, increased resistance to existing antibiotics and emergence of new diseases stimulated the development of ... -
Aqabamycins, Rare Nitro Maleimides and other Novel Metabolites from Microorganisms; Generation and Application of an HPLC-UV-ESI MS/MS Database
(2009-06-04)The battle to improve the quality of life by finding cures against diseases and to extend the life expectancy of mankind is still one of the priorities in natural products chemistry. Al-though ... -
Nafisamycin, Cyclisation Product of a New Enediyne Precursor, Highly Cytotoxic Mansouramycins, Karamomycins Possessing a Novel Heterocyclic Skeleton and Further Unusual Secondary Metabolites from Terrestrial and Marine Bacteria.
(2009-03-19)The search for new medically active compounds to overcome the countless diseases is one of the most relevant objectives worldwide. Medicinal plants were used previously in the traditional ... -
Unusual Sesquiterpenes: Gorgonenes and Further Bioactive Secondary Metabolites Derived from Marine and Terrestrial Bacteria.
(2009-03-16)An increasing number of infectious diseases is still not curable as many organisms are showing antibiotic resistance which urges the development of new medicaments to combat them. Natural ... -
New and Bioactive Secondary Metabolites from Ma-rine and Terrestrial Bacteria: Ramthacin A, B, C, and Polyene Macrolides from Genetically Modified Bacteria
(2009-01-09)Natural products have provided the major sources of chemical diversity for phar-maceutical discoveries for many decades. For clinical application to treat human dis-eases in almost all ... -
Hoch cytotoxisches Kettapetin, Bhimamycine mit ungewöhnlichen Chromophoren und weitere neue Sekundärstoffe aus terrestrischen und marinen Bakterien
(2006-02-27)Nature is a source of medicinal agents since thousands of years, and an impressive number of modern drugs has been isolated from natural habitats, many based on their use firstly in traditional ... -
Aufbau einer HPLC-UV-ESI-MS/MS-Datenbank und ihre Anwendung im Screening arktischer und antarktischer Meeresbakterien
(2005-10-21)Microorganisms from uncommon habitats are an attractive source for chemically and biologically outstanding natural compounds, for the interaction between different species in complex living ... -
Bioactive Secondary Metabolites from Marine and Terrestrial Bacteria: Isoquinolinequinones, Bacterial Compounds with a Novel Pharmacophor
(2005-01-17)After a chemical and biological pre-screening of bacterial extracts, 17 Streptomycetes (including eleven terrestrial and six marine-derived strains) and ten North Sea bacteria (including ... -
Tryptamines as Ligands and Modulators of the Serotonin 5‑HT2A Receptor and the Isolation of Aeruginascin from the Hallucinogenic Mushroom Inocybe aeruginascens
(2005-01-05)Aeruginascin is a natural product from the hallucinogenic mushroom Inocybe aeruginascens. This compound was isolated and identified as 4-phosphoryloxy-N,N,N-trimethyltryptamine. ... -
Untersuchungen zum Sekundärmetabolismus mariner Pilze, Naturstoffscreening und Bioprozessoptimierung mit Hilfe eines kontinuierlichen Bioreaktors
(2004-03-18)The work in hand is divided into three parts: At first the screening of marine microorganisms with the isolation of their metabolites and the solution of the concerning structures. Furthermore ... -
Untersuchungen an Flavonsäurederivaten mit hoher ß-Glukanaffinität
(2003-04-29)For the direct in vivo-detection of deep seated fungal infections a specific radiodiagnostical has been synthesised. Therefore a tyramine derivative of a stilbene-type optical brightener ... -
Untersuchungen zum Sekundärmetabolismus arktischer und antarktischer Meereisbakterien
(2002-09-04)In this work psychrophile bacteria from arctic and antarctic sea-ice were submitted to a chemical and biological screening and due to the results some were examined thoroughly for interesting ... -
Potentiell photochrome brückenkopfsubstituierte Furo[2,3-d]furane
(2002-04-08)Within the scope of this thesis a photochromic system consisting of furo[2,3-d]furans and bis-quinonemethides was investigated. In the literature the known compounds of this system are ...