Browsing Naturwissenschaften, Mathematik und Informatik by Advisor "Salditt, Tim Prof. Dr."
Now showing items 1-20 of 40
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Multi-scale X-ray phase-contrast tomography of the cochlea
(2025-07-04)The organ of Corti in the mammalian cochlea is the receptor organ for hearing, transducing sound into auditory nerve signals. In order to further extend our understanding of the underlying neurophysiology, three dimenstional ... -
3D Virtual Histopathology by Multiscale X-Ray Phase-Contrast Tomography: Novel Tools and Applications
(2025-07-02)Histological analysis has been considered as the gold standard for studying tissue architecture for over two centuries, providing essential insights into tissue morphology and organization. However, the technique is ... -
X-ray Imaging of Cavitation Dynamics with Free-Electron Laser Pulses
(2025-06-25)Cavitation dynamics are fast non-equilibrium hydrodynamic processes involving matter at extreme states. A first relevant mechanism is the light-matter interaction during (ultrafast) laser-induced optical breakdown and ... -
Nuclear Resonances in X-ray Waveguides
(2025-06-12)Hard X-rays generally only interact very weakly with matter, so that tissue, for example, is quite transparent to them. However, this makes the controlled manipulation of X-ray light particularly challenging. While many ... -
A matter of brightness: table-top X-ray generation inside waveguides and X-ray holography with single free-electron laser pulses
(2022-03-22)X-ray microscopy delivers insights into the structure of optically opaque bulk specimens with high spatial resolution. The source brightness poses a limit on the achievable resolution, however. While table-top X-ray sources ... -
Vesicle Adhesion, Fusion, and Neurotransmitter Uptake Studied by Small-Angle X-ray Scattering
(2022-02-15)Synaptic neurotransmission is a highly complex and crucial process in the communication between neuronal cells, and is thus directly related to the complex functions of the neural system, including information processing ... -
Hochauflösende Bildgebung und NEXAFS-Spektroskopie mit weicher Röntgenstrahlung aus laserinduzierten Plasmen
(2019-01-24)Soft x-ray microscopy and absorption spectroscopy are extremely useful tools for high-resolution imaging and chemical analysis of samples in various scientific fields. However, due to the required high photon flux of ... -
Multiscale X-Ray Analysis of Biological Cells and Tissues by Scanning Diffraction and Coherent Imaging
(2018-12-13)The past 70 years of muscle research have profoundly shaped our current understanding of the structure and function of muscle. X-ray diffraction became a key method in its structural analysis and yielded valuable insights ... -
3d virtual histology of neuronal tissue by propagation-based x-ray phase-contrast tomography
(2018-07-05)Deciphering the three-dimensional (3d) cytoarchitecture of neuronal tissue is an important step towards understanding the connection between tissue function and structure and determining relevant changes in neurodegenerative ... -
Time-resolved X-ray phase-contrast tomography
(2018-06-27)X-ray tomography allows to obtain the three-dimensional (3d) structure of weakly interacting objects, such as tissue samples in biomedical imaging or nanoscale structures in materials science, with high spatial resolution. ... -
X-Ray Near-Field Holography: Beyond Idealized Assumptions of the Probe
(2017-11-08)All images are flawed, no matter how good your lenses, mirrors etc. are. Especially in the hard X-ray regime it is challenging to manufacture high quality optics due to the weak interaction of multi-keV photons with matter. ... -
Advanced x-ray multilayer waveguide optics
(2017-09-12)The aim of this thesis is to demonstrate that x-ray waveguide optics can be gen- eralized from a single guiding film to an array of planar waveguides, enabling more complex and controllable phenomena of field propagation ... -
X-Ray Micro- and Nano-Diffraction Imaging on Human Mesenchymal Stem Cells and Differentiated Cells
(2017-06-13)Recent advances in hard x-ray optics, instrumentation and detection have made it possible to probe biological samples by combining diffraction with raster scanning, using step sizes on the order of cellular organelle ... -
X-ray waveguide optics: Beyond straight channels
(2017-04-28)Modern x-ray sources and analysis techniques such as lens less imaging combined with phase retrieval algorithms allow for resolving structure sizes in the nanometerrange. For this purpose optics have to be employed, ... -
Phase retrieval for object and probe in the optical near-field
(2016-01-12)Lensless, holographic X-ray microscopy is a non-invasive imaging technique that provides resolution on the nanometer scale. Therefore, a divergent, coherent and especially clean wavefront impinging on the sample is needed. ... -
Cone-beam x-ray phase-contrast tomography for the observation of single cells in whole organs
(2015-11-10)X-ray imaging enables the nondestructive investigation of interior structures in otherwise opaque samples. In particular the use of computed tomography (CT) allows for arbitrary virtual slices through the object and 3D ... -
Scanning X-Ray Nanodiffraction on Dictyostelium discoideum
(2015-11-06)In the recent years, novel focussing optics for synchrotron radiation sources became available, which now allow focussing the x-radiation down to 100\,nm (FWHM). Thus, the typically poor spatial resolution of Small Angle ... -
Coherent X-Ray Diffractive Imaging on the Single-Cell-Level of Microbial Samples:
(2014-12-17)Since its first experimental demonstration in 1999, Coherent X-Ray Diffractive Imaging has become one of the most promising high resolution X-Ray imaging techniques using coherent radiation produced by brilliant synchrotron ... -
Ein Verfahren zur Herstellung zweidimensionaler Röntgenwellenleiter
(2013-07-15)As X-ray beams only weakly interact with matter, conventional refracting optics are not suitable for the use in this energy range. Instead, different approaches replace conventional optics in the X-ray regime, one of them ... -
A Dedicated Endstation for Waveguide-based X-Ray Imaging
(2012-08-30)X-ray microscopy has emerged as a powerful and versatile imaging technique in many fields of science over the last years, offering insights in opaque media at high spatial resolution. A major challenge remains the ...