Browsing Naturwissenschaften, Mathematik und Informatik by Referee "Bucher, Gregor Prof. Dr."
Now showing items 1-20 of 36
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Characterization of proneural bHLH transcription factor target genes in X. laevis
(2022-09-23)Zc3h12c is a member of the Zc3h12 endoribonuclease family (also known as MCPIP/Regnase), which contains four members (Zc3h12a-c). This family of proteins is characterized by the presence of a single centrally located ... -
Understanding Transcriptional Control During Primordial Germ Cell Differentiation
(2022-07-08)AP2γ, encoded by Tfap2c, is a transcription factor which both represses and activates target gene expression. It is required for the survival of the early mouse embryo; depending on the context of its depletion, the loss ... -
Anti-apoptotic and neuroprotective erythropoietin/CRLF3-signalling in insects and humans
(2022-06-14)The cytokine receptor like factor 3 (CRLF3) evolved together with the eumetazoan nervous system and is present in all major groups of Animalia. Based on sequence similarities, CRLF3 was assigned to the family of class 1 ... -
Glycogen metabolism influences embryonic segmentation and appendages outgrowth during Tribolium castaneum embryogenesis
(2022-02-17)Embryonic segmentation of arthropods is a dynamic biological process that produces an organism by pattern formation, morphogenesis and specification of corresponding cells. The involved genes have mostly been identified ... -
Development of a biotechnologically enhanced sterile insect technique to fight coleopteran pests
(2021-06-30)Tribolium castaneum commonly referred to as the Red Flour Beetle (RFB) belongs to the class Insecta and order Coleoptera, and it’s the best model organism for coleopterans. About 380,000 coleopteran species, constituting ... -
Identification and Characterization of Novel Genes involved in Quinone Synthesis in the Odoriferous Defensive Stink Glands of the Red Flour Beetle, Tribolium castaneum
(2021-05-26)Defense strategies are common in insects including Coleoptera, the largest animal taxon containing various types of beetles. Stink gland secretion of beetles is playing an important role in their defense against detrimental ... -
Development of Transgenic Sterile Insect Technique Strains for the Invasive Fruit Pest Drosophila suzukii
(2020-12-03)Globalization has contributed enormously to emergence and expansion of invasive pests. A recent example is the invasion in Europe and the USA by the cherry vinegar fly Drosophila suzukii. The pest has high potential to ... -
RNA interference: Process and Application to Pest Control
(2020-07-28)Innovation is one of the keys to ensure effective insect pest control in crop protection. A much discussed novelty to insect pest management is represented by RNA interference (RNAi). Employing this conserved virus defense ... -
Pigments, Colours and Patterns - The contribution of eumelanin and pheomelanin to molluscan shell ornamentation with a special focus on the terrestrial snail Cepaea nemoralis
(2020-02-25)In recent years interest into molluscan pigments increased. But a lot of techniques have to be adapted to be usable with often difficult molluscan tissues and shell material. A comprehensive approach needs to encompass ... -
Cortical patterning in syncytial embryos: the link between microtubules and actin cortex
(2020-01-20)Abstract Spatial and temporal regulation of cortical proteins on the cell membrane leads to cortical polarization of cells. After cortical polarization, the cell membrane can divide into different domains such as apical ... -
Functional characterization and molecular identification of neuroprotective receptors for erythropoietin-like ligands
(2019-12-19)The cytokine erythropoietin (Epo) regulates erythropoiesis but also protects mammalian neurons from apoptosis. However, receptors and transduction pathways involved in neuroprotection are only partially characterized. ... -
Non-human primate iPS cells for cell replacement therapies and human cardiovascular disease modeling
(2019-12-03)Induced pluripotent stem cells (iPSC) have revolutionized biomedical research due to their versatility. They have potential for regenerative medicine, drug testing, disease modeling and developmental biology. The development ... -
Behavioual Adaptations to Light Deprivation
(2019-03-20)Similar to most non-sedentary animals, Drosophila shows a wide range of visually guided behaviours and their functionality is crucial for survival. Previous studies showed that visual impairment significantly reduced the ... -
The role of Tc-foxQ2 in the central brain development in Tribolium castaneum
(2019-01-24)The brain is the most complex organ in animals. It controls and coordinates operations like physiology and behavior. The insect brain is built by a conserved set of neuropils which arise from the neuroblasts (NBs). The ... -
Role of Protein phosphatase V in Cell Cycle Control
(2017-08-28)The cell cycle mode is variant among different cell and tissue types and is remodeled during development. This change between modes is referred as cell cycle switch or remodeling. In Drosophila melanogaster, the canonical ... -
Exploring morphological innovation and diversification: Analysis of genes involved in gin-trap formation and antenna remodeling during metamorphosis in Tribolium castaneum
(2017-08-18)How morphological traits originate and diversify is a central question in evolutionary biology. Insects are the most diverse group of animals on the planet and over 80% of insect species belong to the subgroup of holometabola. ... -
Development and application of ontologies for biological applications
(2016-02-08)In the century of information technology automatic processing of knowledge is evolving to be a crucial challenge. However, it is usually not obvious to extract information from the syntax of texts. Hence, ontologies are ... -
Application of RNA Interference for the Study of Lethal Genes and Dynamic Processes
(2016-02-08)RNA interference (RNAi) is a highly conserved cellular mechanism and in the last years it has become to a major tool for functional analyses of genes in different species. Moreover, RNAi has recently been suggested as a ... -
Identification and analysis of novel insect head patterning genes
(2015-09-24)The insect head is a composite structure of several segments and an anterior non-segmental region. Due to head involution, the Drosophila larval head is strongly reduced and for technical reasons the developmental basis ... -
Analyzing the molecular mechanism of Bucky ball localization during germ cell specification in zebrafish
(2015-08-19)Sexual reproducing animals depend on the proper establishment of the germline to ensure the survival of the species by generating fertile progeny. Therefore, many vertebrate and invertebrate species specify their ...