Naturwissenschaften, Mathematik und Informatik
Recent Submissions
-
Multi-omics studies of RNA polymerase II transcription regulation by cyclin-dependent kinases
(2024-10-30)Phosphorylation of the C-terminal repeat domain (CTD) of RNA polymerase II (Pol II) plays a central role in the regulation of gene transcription in eukaryotes. In yeast and mammals, the CTD is highly conserved and consists ... -
Caregiver-child dynamics in early language development: The influence of children’s interests and parental input on children’s word learning
(2024-10-30)Active child views of children’s development postulate that children are active participants in their own learning and development, choosing what information and from whom to learn. More recently, research has demonstrated ... -
Molecular Investigations on Spastic Paresis and Other Inheritable Bovine Diseases
(2024-10-30)Genetic mutations often cause serious diseases associated with severe animal suffering. Today, molecular methods enable efficient research and prevent spreading of disease alleles in cattle populations. The main objective ... -
Manganese and Ruthenium Catalysis for Sustainable C–H Functionalizations and Polymer Synthesis
(2024-10-28)The ever-growing scarcity of resources, energy crises, and environmental pollution demand the development of sustainable chemical processes for C–C bond formations and efficient post-consumer plastic waste recycling. While ... -
Dissecting intraspecific variation in body size related traits in Drosophila melanogaster
(2024-10-23)Understanding the evolution of complex morphological traits is one of the main challenges in biology. This requires the identification of the causative genomic regions and the molecular changes responsible for phenotypic ... -
Bringing Order to the Framework: Nanoscale Charge Transport Characterization of MOFs and COFs
(2024-10-22)Reticular chemistry, the synthesis of highly ordered, porous, crystalline networks with a previously identified target structure, has given rise to various classes of open framework materials, including the best-known ... -
Coordinated Transcriptional Response to Stress-Related Disorders in Multiple Brain Regions: A Spatial and snRNA-sequencing Study in Mice
(2024-10-22)Recent work has demonstrated specific, genome-wide transcriptional changes related to fear and anxiety in rodent animal models and post-mortem human brain samples on the level of individual brain regions and even cell ... -
3d-Metall-Käfig-Komplexe als Modelle für aktive Zentren von nicht-Häm Proteinen
(2024-10-22)This thesis presents a broad study on a new ligand system, specially designed for the mimicry of the quasi-chelating coordination by amino acid side chain residues in enzymatic pockets. The ligand system is based on an ... -
Structure and Kinematics of the Broad-Line Region in Selected Changing-Look AGN
(2024-10-18)In this thesis, the results of three variability studies conducted on three individual active galactic nuclei (AGN) are presented. Each of these AGN belongs to the class of changing-look (CL) AGN, which are characterized ... -
Algorithms for Matching and Analysis Problems on Subsequences
(2024-10-14)The focus of this thesis is on the study of efficient algorithms and computational complexity results for matching and analysis problems on subsequences. The presented results comprise algorithmic solutions and lower ... -
Mycorrhizal mediation of nutrient distribution and stress responses in beech and conifer mixtures
(2024-10-14)With global warming, drought is a rising concern for forests worldwide. In Central Europe, drought has caused severe diebacks of Norway spruce (Picea abies), the most common and economically relevant tree species. ... -
Wachstum und waldbauliche Behandlung der Roteiche (Quercus rubra L.) in Nordwestdeutschland
(2024-10-14)Seventy years after the first monographs on the Northern Red Oak (Quercus rubra L.) for West Germany (Bauer 1953a) and East Germany (Göhre and Wagenknecht 1955) were published, this work is once again devoted to growth, ... -
The role of pragmatics in early word learning
(2024-10-10)Young children show remarkable abilities in learning words from highly ambiguous surroundings. Regardless how many languages they learn, they seem to have no effort in linking a novel word to its correct meaning. ... -
Utilizing HPC Systems to Serve Compute-Intensive Tasks from a Data Lake Managing Sensitive Data
(2024-10-10)Data lakes have been proposed by James Dixon in 2010 to prevent information loss happening during the extract-transform-load process usually employed to ingest data into a data warehouse. Instead, he proposed a schema-on-read ... -
Exploring Stickiness in CAT(κ) Spaces
(2024-10-10)The Fréchet mean is a natural generalization of the expectation to probability distributions on arbitrary metric spaces. In recent years, several seemingly related phenomena were observed for certain distributions on ... -
Improving the wellbeing of smallholder coffee farmers at Masaba (Mount Elgon) in Uganda: An investigation of challenges and resources
(2024-10-08)The coffee sector in Uganda is of great socio-economic importance for the country. For many smallholder farmers in the Masaba region (Mount Elgon) in Uganda, the cultivation of Arabica coffee is the most important source ... -
Novel machine learning solutions for precision medicine - from causal inference to cellular perturbations and interactions
(2024-10-04)Optimal therapy of complex diseases necessitates a shift from one-size-fits-all solutions towards personalized treatment plans. To achieve this, it is crucial to understand the casual effect of medical interventions, such ... -
Mechanistic Studies on flat and stepped Palladium Single Crystal Surfaces: Experimental Evidence of Reaction Intermediates for the Decomposition of Formic Acid and Oxidation of Ammonia
(2024-10-04)In this work, experimental and theoretical investigations of formic acid desorption, decomposition and ammonia oxidation on single crystal palladium surfaces are presented. The formic acid system is investigated using a ... -
Economic implications of tree species composition and structural diversity in European beech stands enriched with coniferous trees
(2024-09-27)Central European forests are the result of centuries of human activity. Changes in species composition, mainly by introducing conifers to areas outside their native range, mostly Norway spruce (Picea abies [L.] Karst.; ... -
Inter and intra-specific interaction effects on individual tree architecture and stand structure, and consequences for ecosystem functions in mixed forests
(2024-09-27)Central Europe is predicted to experience an increase in temperatures and storm frequency and intensity, which will impact forest ecosystems directly and in interaction. European forests host a large share of Europe’s ...