Naturwissenschaften, Mathematik und Informatik
Recent Submissions
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Challenges and Opportunities for Smallholder Farmers in Oil Palm Replanting: Evidence from Indonesia
(2025-02-14)The cultivation of oil palm supports the livelihoods of millions, including smallholder farmers. However, studies have shown that smallholder-managed plantations still generate much lower yields than large-scale company-managed ... -
Optimising management strategies on permanent grassland in the temperate zone in order to increase carbon sequestration, meet yield demands and ensure resilience to future climate change
(2025-02-14)Future climate change will require agricultural management to adapt to increasing air temperatures and changing precipitation patterns while simultaneously providing food, fodder and biomass, and maintaining a variety of ... -
Crop rotational effects on soil structure, root development and yield formation of winter wheat
(2025-02-14)Winter wheat (Triticum aestivum L.) is one of the most important staple food crops worldwide and commonly grown in crop rotations to obtain high grain yields and overcome increased disease pressure which is caused by ... -
Fundamental Changes in Food: Improving the Toolbox of Simulation Modeling
(2025-02-14)Background The global agrifood system is critically contributing to the transgression of planetary boundaries (Rockström et al., 2009b, 2009a). Crippa et al. (2021) estimate that the agrifood system contributes 34% of ... -
The roles of long non-coding RNAs in CNS diseases with a focus on astroglial-neuronal communication
(2025-02-14)Aging is accompanied by a decline of cognitive functions and represents a major risk factor for the development of neurodegenerative diseases such as Alzheimer’s disease (AD). Key pathological changes linked to AD are the ... -
A nidulans development and secondary metabolism requires coordinated VeA nuclear import and export
(2025-02-14)Survival of multicellular organisms requires the functional interplay between complex regulatory networks including gene expression, the ubiquitin proteasome protein degradation system, and intracellular transport control. ... -
Identification and Characterization of Intermediates in Transmetalation Reactions from Boron to Lithium and Copper
(2025-02-14)Transmetalation is a crucial elementary step in cross-coupling reactions. In this context, boron nucleophiles are especially popular and versatile, however, the fundamental details of transmetalation reactions involving ... -
Investigation of Framework-forming Aggregation of Peptide Helices on Membrane Surfaces
(2025-02-14)This study presents the development and investigation of peptide-based systems designed to induce controlled aggregation on membrane surfaces, potentially facilitating cell signaling by promoting lipid raft formation. The ... -
Poplar Responses to Nutrient Deficiency and Drought as Affected by Different Ectomycorrhizal Fungal Species
(2025-02-14)Nutrient imbalances and drought are challenges the world’s forests are currently facing due to massively changing environmental conditions. In European forests, phosphorus (P) nutrition is declining due to increasing ... -
Sensory processing and learning in spiking neural networks
(2025-02-12)Organisms are capable of navigating an extremely complex environment with the help of their senses. To do this, they exploit that high dimensional sensory inputs can often be predicted from relatively sparse information, ... -
(Mis)Guiding consumers to sustainable consumption: the role of information, labels and claims
(2025-02-06)This dissertation uses plant-based meat and dairy alternatives (PBMDAs) as a food category example, and palm oil as a case study ingredient, to illustrate how consumer communication on food products can influence assumptions ... -
MINFLUX nanoscopy deep in (living) brain tissue
(2025-02-06)Optical fluorescence microscopy offers intrinsic advantages that enable imaging in tissue, such as non-invasiveness and specificity of the fluorescence signal. However, the resolution and thus the information content ... -
Development of a Bone Adhesive Material based on Diazirinyl-Collagen Mimetic Peptides
(2025-02-05)The treatment of small and inaccessible bone fractures with metallic implants is challenging. One potential solution to this issue is the use of an adhesive to adhere the affected fragments. In the search for new biocompatible ... -
Alpha-synuclein amyloid aggregation: From basic to translational research
(2025-02-05)Neurodegenerative diseases are a heterogeneous group of disorders affecting the lives of millions of people worldwide. A shared pathologic hallmark is the appearance of insoluble aggregates in the brain. The components of ... -
On the chemistry of sulfur: Development of NOS bridge model systems and Stereoretentive 2,3-bis(trifluoromethyl)cyclopropanation of heteroarenes via sulfonium salts
(2025-02-05)This thesis presents research conducted across two distinct projects in sulfur chemistry. The first project focused on the synthesis of model systems based on biphenyl, xanthene, and triazamacrocyclic scaffolds to investigate ... -
Single-cell studies of mammalian ovaries
(2025-01-31)Ovarian aging progresses more rapidly than in other organs. Female fertility declines exponentially after the age of 35, and as women increasingly delay childbearing, it is paramount to understand the underlying etiology ... -
Proteogenomic peptide discovery in large search spaces
(2025-01-30)Novel peptide and protein discovery is of therapeutical relevance and ignited the development of methods for their identification, commonly done via mass spectrometry. The latter relies on a well-characterised proteogenomic ... -
Enantioselective Synthesis and Postsynthetic Functionalization of Thiahelicenes and their Oxa-analogues
(2025-01-30)Based on the Alcarazo group’s experience in enantioselective Au(I)-catalyzed synthesis of (hetero)helicenes employing alkyne hydroaryration reactions, the gold precatalyst 188c, combining a chiral BINOL-derived backbone ... -
Quantitative Estimation of Cell Mechanical Cues using Elastic Micropillars
(2025-01-24)Within the intricate landscape of the cellular microenvironment, the inter- play between biochemical and physical signaling emerges as a decisive force shaping the physiology and functions of living cells. Recent insights ... -
Microbial Communities in the Terrestrial Subsurface
(2025-01-23)Terrestrial subsurface habitats represent a significant portion of Earth's prokaryotic biomass. However, our understanding of microbial diversity and functions in these environments, particularly in arid regions, remains ...