Naturwissenschaften, Mathematik und Informatik
Recent Submissions
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The role of chromatin hubs in the regulation of gene expression and maintenance of genomic integrity
(2025-03-20)The correct development and functioning of complex organisms rely on precise spatiotemporal regulation of gene expression and on efficient maintenance of their genomic stability. Regulation of gene expression during ... -
Stability and evolution of non-equilibrium states in the iron carbon system
(2025-03-20)The engineering of metastable microstructures has opened new avenues in advanced materials development. In Fe-C-based alloys, the drastic reduction in carbon solubility during the fcc-to-bcc transformation, in combination ... -
The Melody of Miscommunication in the Heart Decoding LZTR1 deficiency with a Multicellular Focus
(2025-03-20)LZTR1 deficiency is a known cause of Noonan syndrome (NS) and is linked to early-onset and severe hypertrophic cardiomyopathy (HCM). Despite the recognized importance of paracrine communication in cardiac pathology, the ... -
Fast inference in flexible high dimensional models of gene co-expression and genotype-gene expression interaction
(2025-03-20)As more high-throughput sequencing data is produced from ever-growing human cohorts, understanding human biology becomes a more and more quantitative and statistical task. Starting notably with the data made available in ... -
Deep Probabilistic Priors for Solving Inverse Problems
(2025-03-20)Inverse problems are problems where causal sources are inferred from observed effects. They are ubiquitous in science and engineering. Examples include image reconstruction from neural responses, feature visualizations of ... -
Synthesis of Pyrrolo[1,2-c]pyrimidine-1-ylidenes: Coordination Chemistry and Application as Ancillary Ligands for Metal Catalysis
(2025-03-20)N-heterocyclic carbenes (NHCs) represent an important class of ancillary ligands for transition metal catalysis due to their strong binding character and generally simple syntheses procedures. One important feature of these ... -
Cooperative Activation of Small Molecules on Preorganized Dinuclear Cobalt Complexes
(2025-03-14)The coordination chemistry of late-transition-metal dinitrogen complexes remains a topic of considerable interest. In this study, a pyrazolate-based dinucleating nacnac ligand was employed to construct a series of bimetallic ... -
Reconstitution and molecular characterisation of the mitochondrial membrane contact site
(2025-03-14)Due to their endosymbiotic origin, mitochondria of eukaryotic cells are enveloped by two membranes. While the outer membrane is rather flat, the inner membrane is intricately folded into subcompartments called cristae. ... -
Novel methods for the next generation of high-energy physics event generators
(2025-03-14)Monte Carlo event generators are crucial for the success of the LHC physics program and provide accurate theory predictions for various applications. As experiments become more precise and undergo upgrades, event generators ... -
Cell-Substrate Distance Fluctuations and their Impact on Wound Healing in Epithelial Tissues
(2025-03-13)Cellular movements are fundamental to a wide array of physiological processes essential for an organism's development, maintenance, and repair. Understanding the underlying mechanisms that regulate these movements provides ... -
Conservation of wild bees in agricultural landscapes through intercropping and habitat management
(2025-03-12)Bees, important providers of vital environmental functions such as pollination and soil bioturbation, are currently declining both on a local and global scale. Two main causes of this decline are habitat loss and fragmentation ... -
Characterisation of exoplanet atmospheres with high-resolution spectroscopy
(2025-03-07)High-resolution spectroscopic observations offer a powerful approach to investigate planetary atmospheric composition and dynamics. Absorption and emission spectral lines serve as valuable diagnostics, as their strength, ... -
Probing Feebly Interacting Dark Matter
(2025-03-07)Feebly Interacting Massive Particles are elusive Dark Matter candidates produced via the freeze-in mechanism. They are a type of Dark Matter that never reaches thermal equilibrium with the Standard Model. This fact leads ... -
Development of a rapid in-field method for measuring soil pH and plant-available nutrients using ISFET multi-sensors
(2025-03-07)Knowledge of plant-available soil nutrients is important for determining fertilizer requirements. Collecting this data rapidly and directly in the field could be beneficial for improving nutrient utilization efficiency. ... -
Identification of resistance parameters / mechanisms of sugar beet (Beta vulgaris) to green peach aphid Myzus persicae and black bean aphid Aphis fabae
(2025-03-07)The infestation of two aphid species, the green peach aphid (Myzus persicae) and black bean aphid (Aphis fabae), along with the viruses they transmit, causes significant yield losses in sugar beet (Beta vulgaris). With ... -
Hydrogeological Insights into Complex Fractured-Porous Media and Karst Systems: Innovative Methods for Modeling, Characterization, and Environmental Assessment
(2025-03-07)This thesis provides an in-depth, multi-scale exploration of partially saturated flow and transport dynamics in complex porous-fractured systems and fracture networks. Focusing on the complexities of gravity-driven flows, ... -
Multifaceted Diversity in Forest Ecosystems Worldwide
(2025-02-25)Earth’s biodiversity faces numerous threats that endanger the delicate balance of ecosystems, highlighting the urgent need for integrated conservation strategies to preserve biodiversity. Forests in particular are critical ... -
Landscape Moderation of Ecological Patterns and Processes
(2025-02-25)This dissertation studies landscape moderation of ecological patterns and processes by employing different modeling approaches to investigate how landscape patterns influence ecological processes and, reversely, how ... -
Messung der Wandschubspannung in Strömungen mit Stoß-Grenzschicht-Wechselwirkungen
(2025-02-24)In supersonic flight, shock-boundary layer interactions (SBLI) have a considerable influence on the performance and structural requirements of missiles and airplanes. The fundamental prediction of the acting forces and ... -
The generation and dynamic control of neural activity sequences
(2025-02-24)Our behavior and cognition is flexible and dynamic. With ease, we can switch between different thoughts, memories, and movements. We are able to dynamically adapt individual behaviors, like the speed and path our arm takes ...