Investigations towards the design, synthesis and application of new sulfur-based transfer reagents
von Bernd Waldecker
Datum der mündl. Prüfung:2019-05-02
Erschienen:2019-06-20
Betreuer:Prof. Dr. Manuel Alcarazo
Gutachter:Prof. Dr. Manuel Alcarazo
Gutachter:Prof. Dr. Lutz Ackermann
Gutachter:Prof. Dr. Dietmar Stalke
Gutachter:Dr. Shoubhik Das
Gutachter:Dr. Franziska Thomas
Gutachter:Dr. Max Hansmann
Dateien
Name:BerndWaldeckerDissertation2019.pdf
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Zusammenfassung
Englisch
New dibenzothiophenium-based alkynylation reagents were prepared and their versatile reactivity was demonstrated in reactions with benchmark C-, S-, N- and P-nucleophiles. Straightforward experiments applying 13C-labeled reagents were proceeded to give a first insight in the reaction mechanism of the transfer reaction. Furthermore, the reagents were directly compared with their commercially available EBX analogues highlighting them as powerful and safe alternative to hypervalent iodine reagents.
Keywords: sulfur chemistry; electrophilic alkynylation; isotopic labeling; alkynes