Iron-Catalyzed C–H/N–H Activations for Annulation of Allenes, Alkynes, and Bicyclopropylidenes
von Jiayu Mo
Datum der mündl. Prüfung:2020-10-26
Erschienen:2020-11-16
Betreuer:Prof. Dr. Lutz Ackermann
Gutachter:Prof. Dr. Lutz Ackermann
Gutachter:Dr. Alexander Breder
Gutachter:Prof. Dr. Dr. Lutz Tietze
Gutachter:Prof. Dr. Marina Bennati
Gutachter:Prof. Dr. Ricardo Mata
Gutachter:Dr. Johannes Jun.-prof. Walker
Dateien
Name:Disertation Jiayu Mo-Final-ediss.pdf
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Description:Iron-Catalyzed C–H/N–H Activations for Annulation of Allenes, Alkynes, and Bicyclopropylidenes
Zusammenfassung
Englisch
Iron-catalyzed C–H/N–H activations for the annulation of allenes, alkynes, and bicyclopropylidenes were realized by using a customizable clickable triazole amide under mild reaction conditions. The powerful iron catalysis occurred under external‐oxidant‐free conditions even at room temperature. A unifying mechanistic approach combining experiments, Mössbauer spectroscopy was employed to delineate the reaction mechanisms. The synthetic utility of the iron‐catalyzed oxidant‐free C−H functionalizations was illustrated by the traceless removal of the modular TAH/TAM group in a user‐friendly fashion.
Keywords: Iron; C–H Activation; Allenes; Bicyclopropylidenes; alkynes; redox-neutral reactions