Kathodale transkranielle Stromstimulation des visuellen Kortex als Verfahren zur prophylaktischen Behandlung der Migräne

Kriener, Naomi

dc.contributor.advisor	Antal, Andrea Prof. Dr.
dc.contributor.author	Kriener, Naomi
dc.date.accessioned	2021-03-19T15:37:49Z
dc.date.available	2021-03-31T00:50:19Z
dc.date.issued	2021-03-19
dc.identifier.uri	http://hdl.handle.net/21.11130/00-1735-0000-0005-15B4-8
dc.identifier.uri	http://dx.doi.org/10.53846/goediss-8496
dc.language.iso	deu	de
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.ddc	610	de
dc.title	Kathodale transkranielle Stromstimulation des visuellen Kortex als Verfahren zur prophylaktischen Behandlung der Migräne	de
dc.type	doctoralThesis	de
dc.title.translated	Cathodal transcranial direct current stimulation of the visual cortex in the prophylactic treatment of migraine	de
dc.contributor.referee	Antal, Andrea Prof. Dr.
dc.date.examination	2021-03-24
dc.description.abstracteng	The purpose of this study was to determine whether transcranial direct current stimulation (tDCS) can be an effective prophylactic therapy for migraine and migraine-associated pain. This painless and non-invasive method was applied for 6 weeks over the visual cortex (V1), delivered three times per week. Thirty patients were assigned to cathodal or to sham stimulation, and 26 patients participated in the final analyses (cathodal: n = 13, sham: n = 13). During the first 3 weeks both groups received only placebo stimulation. Measures of attack frequency and duration, intensity of pain and number of migraine-related days were recorded 2 months before, during and 2 months post-treatment. Patients treated by cathodal tDCS showed a significant reduction in the duration of attacks, the intensity of pain and the number of migraine-related days post-treatment as compared to the baseline period, but not in the frequency of the attacks. However, compared to the sham group, only the intensity of the pain was significantly reduced post-stimulation. No patients experienced severe adverse effects. Our results suggest that the application of cathodal stimulation over the V1 might be an effective prophylactic therapy in migraine, at least with regard to pain control.	de
dc.contributor.coReferee	Erlenwein, Joachim PD Dr.
dc.subject.ger	kathodal	de
dc.subject.ger	Migräne	de
dc.subject.ger	Schmerz	de
dc.subject.ger	V1	de
dc.subject.ger	tDCS	de
dc.subject.eng	cathodal	de
dc.subject.eng	migraine	de
dc.subject.eng	pain	de
dc.subject.eng	V1	de
dc.subject.eng	tDCS	de
dc.identifier.urn	urn:nbn:de:gbv:7-21.11130/00-1735-0000-0005-15B4-8-3
dc.affiliation.institute	Medizinische Fakultät	de
dc.subject.gokfull	Medizin (PPN619874732)	de
dc.subject.gokfull	Neurologie - Allgemein- und Gesamtdarstellungen (PPN619876247)	de
dc.description.embargoed	2021-03-31
dc.identifier.ppn	1751904938

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Human- und Zahnmedizin [2871]

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