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dc.contributor.advisor Feltgen, Nicolas Prof. Dr.
dc.contributor.author Khattab, Mohammed Haitham
dc.date.accessioned 2021-03-23T15:21:09Z
dc.date.available 2021-04-01T00:50:05Z
dc.date.issued 2021-03-23
dc.identifier.uri http://hdl.handle.net/21.11130/00-1735-0000-0008-57C7-6
dc.language.iso eng de
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.ddc 610 de
dc.title Functional changes in surgical treatment of epiretinal membrane de
dc.type doctoralThesis de
dc.contributor.referee Feltgen, Nicolas Prof. Dr.
dc.date.examination 2021-03-25
dc.description.abstracteng With the increasing aging in our society, ERM represents one of the treatable causes of vi-sion impairment, especially in elderly people. Patients with ERM present with reduced and distorted vision, metamorphopsia, and nonspecific visual disturbances. The diagnosis of the ERM is based on clinical finding, mainly on a dilated fundus examination or fundus pho-tograph. A qualitative and quantitative analysis of the retina can nowadays be ob-tained using OCT cross-sectional images. ERM can be surgically well manageable with con-sequent reduction of metamorphopsia and improvement in vision. Despite all of the innovations in the field of vitreoretinal surgery, currently, there is not any possibility to capture the extent of the distortion, while other subjective testing methods such as visual acuity and central visual field, can be quantified. The study demonstrated that the new AMD® test can be used in clinical setting to detect and quantify the severity of metamorphopsia in patients with ERM. Moreover, a computer or mobile application for the AMD® test allows self-monitoring at home, which could strengthen the patient’s self-efficacy and has good promise of detecting metamorphopsia in the future. Especially taken into account the current situation with COVID-19 pandemic, when doctor visit is not alawys possible, in this case patients can monitor themselves at home and visit the ophthalmologist only when the score is changed. In this study, the degree and severity of metamorphopsia in patients with ERM pre- and postoperatively was quantified using the AMD® test. Results showed a significant and con-tinuous improvement in visual acuity and in metamorphopsia postoperatively. The metamorphopsia is a new clinical aspect, which could be used besides the visual acuity in observing operation outcomes and follow-up patients. To the best of our knowledge, no other studies have yet quantified the metamorphopsia using the AMD® test in patients with ERM. Larger studies with longer observation periods are crucial to evaluate the long-term morphological changes of metamorphopsia in patients with ERM. de
dc.contributor.coReferee Gollisch, Tim Prof. Dr.
dc.subject.eng Metamorphopsia de
dc.subject.eng Epiretinal Membrane de
dc.subject.eng Pars Plana Vitrectomy de
dc.subject.eng A Metamorphopsia Detector de
dc.identifier.urn urn:nbn:de:gbv:7-21.11130/00-1735-0000-0008-57C7-6-6
dc.affiliation.institute Medizinische Fakultät de
dc.subject.gokfull Medizin (PPN619874732) de
dc.description.embargoed 2021-04-01
dc.identifier.ppn 1752292413

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