Untersuchung der klinischen Anwendbarkeit der volumetrischen Kapnometrie bei Hochfrequenz-Oszillationsbeatmung (HFOV) im ARDS-Großtiermodell

Untersuchung der klinischen Anwendbarkeit der volumetrischen Kapnometrie bei Hochfrequenz-Oszillationsbeatmung (HFOV) im ARDS-Großtiermodell

Study of Clinical Application of Volumetric Capnometry During High-Frequency Oscillatory Ventilation (HFOV) in a Large Animal Model of ARDS

Thomas Schneidereit

Doctoral thesis

Date of Examination: 2021-04-29

Date of issue: 2021-04-23

Advisor: Mörer, Onnen Prof. Dr.

Referee: Mörer, Onnen Prof. Dr.

Referee: Danner, Bernhard Prof. Dr.

Persistent Address: http://hdl.handle.net/21.11130/00-1735-0000-0008-5803-2

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Abstract

English

As the first in vivo study, this dissertation and animal experiments investigate the application of volumetrical capnometry during HFOV in an ARDS large animal model. We could demonstrate that the method is applicable and that the measured CO2 excretion is correlating not only with CO2 partial pressure in the blood gas analyses, but also can used as viable factor in predicting changes in lung volume.

Keywords: Volumetric Capnometry; HFOV; ARDS; Capnometry; Predicted Lung Volume

Schlagwörter: Volumetrische Kapnometrie; HFOV; ARDS