dc.contributor.advisor | Diederichsen, Ulf Prof. Dr. | |
dc.contributor.author | Nasufovska, Atida | |
dc.date.accessioned | 2021-10-21T12:27:47Z | |
dc.date.available | 2021-10-27T00:50:08Z | |
dc.date.issued | 2021-10-21 | |
dc.identifier.uri | http://hdl.handle.net/21.11130/00-1735-0000-0008-5950-A | |
dc.identifier.uri | http://dx.doi.org/10.53846/goediss-8897 | |
dc.language.iso | eng | de |
dc.publisher | Niedersächsische Staats- und Universitätsbibliothek Göttingen | de |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.subject.ddc | 540 | de |
dc.title | Prebiotic Synthesis of Inorganic Pyrophosphate (PPi) Driven by a Geochemical Redox Reaction | de |
dc.type | doctoralThesis | de |
dc.contributor.referee | Diederichsen, Ulf Prof. Dr. | |
dc.date.examination | 2021-09-10 | |
dc.description.abstracteng | In all extant organisms adenosine triphosphate (ATP) is the energy carrier and transmitter of free energy from exergonic to endergonic processes. Since ATP is a complex molecule, it was unlikely available on prebiotic Earth. Proposed pyrophosphate (PPi) with energy-rich phosphoanhydride bond was considered as plausible energy-source on early Earth. In this thesis, a synthesis of PPi under prebiotic conditions is indicated by condensation of orthophosphate (Pi) in aqueous solution. Furthermore, attempts were made towards synthesizing a peptidic minimal model of the active site A-Cluster in acetyl CoA synthase (ACS), which is a key enzyme in combination with carbon monoxide dehydrogenase (CODH) in ancient WOOD-LJUNGDAHL pathway. | de |
dc.contributor.coReferee | Fritz, Hans-Joachim Prof. Dr. | |
dc.subject.ger | Origin of Life | de |
dc.subject.ger | Origin of Life | de |
dc.subject.eng | Prebiotic Chemistry | de |
dc.subject.eng | Prebiotic Chemistry | de |
dc.identifier.urn | urn:nbn:de:gbv:7-21.11130/00-1735-0000-0008-5950-A-5 | |
dc.affiliation.institute | Fakultät für Chemie | de |
dc.subject.gokfull | Chemie (PPN62138352X) | de |
dc.description.embargoed | 2021-10-27 | |
dc.identifier.ppn | 1774730138 | |