dc.contributor.advisor | Behme, Daniel PD Dr. | |
dc.contributor.author | Möller, Cathrin | |
dc.date.accessioned | 2022-01-14T10:36:50Z | |
dc.date.available | 2022-02-03T00:50:08Z | |
dc.date.issued | 2022-01-14 | |
dc.identifier.uri | http://hdl.handle.net/21.11130/00-1735-0000-0008-59F1-4 | |
dc.identifier.uri | http://dx.doi.org/10.53846/goediss-9042 | |
dc.language.iso | deu | de |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.subject.ddc | 610 | de |
dc.title | Sensitivität und Spezifität der Detektion von Vasospasmen nach SAB mittels früharterieller CTP-basierten 4D-CTA-Rekonstruktionen sowie konventioneller CTA | de |
dc.type | doctoralThesis | de |
dc.title.translated | Sensitivity and Specificity of the Detection of Vasospasm after SAH by CTP-based 4D-CTA-Reconstruction and conventional CTA | de |
dc.contributor.referee | Behme, Daniel PD Dr. | |
dc.date.examination | 2022-01-26 | |
dc.description.abstracteng | Cerebral vasospasm frequently occur after aneurysmal subarachnoid hemorrhage (aSAH) and are a major contributor to mortality and morbidity following aSAH.
Their diagnosis is a challenge which comes with a significant radiation exposure due to repeated CTA and CTP scans.
In this work, I investigate the diagnostic performance of 4D-CTA reconstructed from the CTP dataset in relation to conventional CTA.
I performed a retroscpective analysis of patients with aSAH who received endovascular intervention as a rescue treatment for vasospam.
Considering digital subtraction angiography as gold standard, I estimated sensitivity, specificity, and interrater reliability for 4D-CTA and conventional CTA.
I found no evidence that early-phase 4D-CTA performs significantly worse than conventional CTA by any characterization, and in many cases performs significantly better.
This study suggests that CTA scans could be replaced by 4D-CTA reconstructed from the CTP dataset, thereby reducing radiation exposure. | de |
dc.contributor.coReferee | Mielke, Dorothee Prof. Dr. | |
dc.subject.eng | SAH | de |
dc.subject.eng | vasospasm | de |
dc.subject.eng | CTA | de |
dc.subject.eng | CTP | de |
dc.identifier.urn | urn:nbn:de:gbv:7-21.11130/00-1735-0000-0008-59F1-4-8 | |
dc.affiliation.institute | Medizinische Fakultät | de |
dc.subject.gokfull | Neurologische Diagnostik, Neuroradiologie (PPN619876263) | de |
dc.subject.gokfull | Medizin | de |
dc.description.embargoed | 2022-02-03 | |
dc.identifier.ppn | 178619712X | |