Funktionelle und onkologische Resultate der transoralen Laserchirurgie beim Zungengrundtumor

Funktionelle und onkologische Resultate der transoralen Laserchirurgie beim Zungengrundtumor

Oncologic and functional results after transoral laser microsurgery of tongue base carcinoma

Mei Iskandar

Doctoral thesis

Date of Examination: 2015-12-10

Date of issue: 2015-12-10

Advisor: Canis, Martin Prof. Dr.

Referee: Canis, Martin Prof. Dr.

Referee: Wolff, Hendrik PD Dr.

Persistent Address: http://hdl.handle.net/11858/00-1735-0000-0028-8669-1

Files in this item

Name: Funktionelle und onkologische Resultate der transoralen Laserchirurgie beim Zungenrundtumor.pdf

Size: 691,2 KB

Format: PDF

View/Open

The following license files are associated with this item:

Creative Commons

Abstract

English

In this present study 82 patients with previously untreated squamous cell carcinoma of the tongue base (T1-4, N0-2, M0) underwent transoral laser surgery with curative intent between 1986 and 2011. 5-year overall survival and recurrence-free survival was 59% and 69%, respectively. In 11 (13%) patients local recurrence occurred. Primary transoral laser microsurgery in combination with adjuvant radio(chemo)therapy is an efficient treatment for early stages and advanced tongue base carcinoma that achieves good local control and overall-survival rates. Compared with primary high-dose radio(chemo)therapy it offers better oncologic results combined with significantly lower functional deficits and fewer side-effects. Compared with conventional surgery, transoral laser microsurgery shows less inherent complications. Hence, multimodal treatment can be advantageous and should be considered for all advanced stages to achieve maximum disease control.

Keywords: transoral laser surgery; squamous cell; carcinoma of the tongue base