Funktionelle und onkologische Resultate der transoralen Laserchirurgie beim Zungengrundtumor

Oncologic and functional results after transoral laser microsurgery of tongue base carcinoma

by Mei Iskandar
Doctoral thesis
Date of Examination:2015-12-10
Date of issue:2015-12-10
Advisor:Prof. Dr. Martin Canis
Referee:Prof. Dr. Martin Canis
Referee:PD Dr. Hendrik Wolff
Persistent Address: http://dx.doi.org/10.53846/goediss-5418

 

 

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Abstract

English

In this present study 82 patients with previously untreated squamous cell carcinoma of the tongue base (T1-4, N0-2, M0) underwent transoral laser surgery with curative intent between 1986 and 2011. 5-year overall survival and recurrence-free survival was 59% and 69%, respectively. In   11   (13%)   patients   local recurrence occurred.  Primary transoral laser microsurgery in combination with adjuvant radio(chemo)therapy is an efficient treatment for early  stages and advanced tongue base carcinoma that achieves good local control and overall-survival rates. Compared with primary high-dose radio(chemo)therapy it offers better oncologic results combined with significantly lower functional deficits and fewer side-effects. Compared with conventional surgery, transoral laser microsurgery shows less inherent complications. Hence, multimodal treatment can be advantageous and should be   considered   for   all   advanced   stages   to   achieve   maximum   disease   control.
Keywords: transoral laser surgery; squamous cell; carcinoma of the tongue base
 
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