Prävalenz und klinische Relevanz enoraler Mykosen und Dermatokyosen bei Bewohnern in pflegerischen Versorgungseinrichtungen

Prävalenz und klinische Relevanz enoraler Mykosen und Dermatokyosen bei Bewohnern in pflegerischen Versorgungseinrichtungen

Prevalence and relevance of fungal infections in nursing homes

Wojak, Klaus-Peter

Dissertation

Angenommen am: 2016-09-19

Erschienen: 2016-08-29

Betreuer: Nauck, Friedemann Prof. Dr.

Gutachter: Reichard, Utz Prof. Dr.

Gutachter: Mausberg, Rainer Prof. Dr.

Zum Verlinken/Zitieren: http://hdl.handle.net/11858/00-1735-0000-0028-8815-D

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Name: dissertation Wojak 20160815.pdf

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Zusammenfassung

Englisch

Other studies showed that the risk for a fungal infection is higher for elderly people. Furthermore we know based on different studies that there is a correlation between enoral symptoms like a dry mouth and fungal colonization of the oral cavity. Based on these findings, we hypothesize that the modified quality and integrity of the human skin and mucosa in the elderly might be associated with a significant increase of fungal colonization or infection. To test this hypothesis, different populations of older patients and individuals are compared with a control group of young healthy medical students. Our study includes 3 different care facilities. Swabs from the oral cavity, the inguinal fold and foot interdigital area of every patient have to be analysed. Anamnestic data as well as data on antibiotic usage, personal hygiene and food habits are obtained and clinical inspection of the oral cavity and other anatomical regions of these study groups are done. More than 70% of the participants were colonized with fungi (76% in nursing homes, 47% in the control group). A fungal colonization was significantly more often found in the oral cavity of elderly individuals. Non-albicans-species with a resistance against Azol-antimycotics, were more often found in the oral cavity of the study group whereas candida albicans was the most common species especially in the oral cavity of the younger control group. Elderly people wearing dentures showed a statistic correlation to non-albicans-species. There is no difference of fungal colonization detectible between the study groups and the control group in reference to the inguinal and interdigital swabs. There was no significant difference concerning the gender. In summary the results confirmed our hypothesis that fungi are more often found in the oral cavity of elderly individuals.

Keywords: fungal infection; nursing home

Schlagwörter: Mykose; pflegerische Versorgungseinrichtungen