Bioinspired dioxygen activation with copper complexes supported by Bis(oxazoline) and Bis(benzimidazole) ligands
von Guillermo Duran Solares
Datum der mündl. Prüfung:2023-05-24
Erschienen:2023-06-20
Betreuer:Prof. Dr. Franc Meyer
Gutachter:Prof. Dr. Manuel Alcarazo
Gutachter:Prof. Dr. Wesley Browne
Gutachter:Prof. Dr. Konrad Koszinowski
Gutachter:Prof. Dr. Lisa Vondung
Gutachter:Dr. Michael John
Dateien
Name:Thesis_Guillermo DS.pdf
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Description:PhD Thesis_Guillermo DS
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Zusammenfassung
Englisch
Many synthetic complexes modeling the oxy form of the tyrosinase have been developed and have shown a preference for either the side-on peroxodicopper(II) (P) or the bis(-oxo)dicopper(III) (O) core depending on the supporting ligand, the solvent and the nature of counterions. In view of the potential of bioinspired copper complexes to serve as catalysts for selective oxidations of organic substrates, elucidating the factors that govern the interconversion of these P and O intermediates and their distinct reactivity patterns is of great interest. Recently we initiated the use of bis(oxazoline) (BOX) ligands in Cu/O2 chemistry and we demonstrated that their P and O cores can be interconverted by peripheral (de)protonation events at the ligand backbone. We have now studied the reactive [Cu2O2] intermediates of a variety of different bis(oxazoline) (BOX) and bis(benzimidazole) (BBIM) ligands, their formation kinetics and acid/base induced P/O interconversion, as well as their reactivity towards substrates.
Keywords: Dinuclear Complex; Oxygen activation; Interconversion; Kinetics; Peroxo /bis(n-oxo); BOX; Bis(benzimidazole) lignads