Naturwissenschaften, Mathematik und Informatik
Recent Submissions
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Sensory processing and learning in spiking neural networks
(2025-02-12)Organisms are capable of navigating an extremely complex environment with the help of their senses. To do this, they exploit that high dimensional sensory inputs can often be predicted from relatively sparse information, ... -
(Mis)Guiding consumers to sustainable consumption: the role of information, labels and claims
(2025-02-06)This dissertation uses plant-based meat and dairy alternatives (PBMDAs) as a food category example, and palm oil as a case study ingredient, to illustrate how consumer communication on food products can influence assumptions ... -
MINFLUX nanoscopy deep in (living) brain tissue
(2025-02-06)Optical fluorescence microscopy offers intrinsic advantages that enable imaging in tissue, such as non-invasiveness and specificity of the fluorescence signal. However, the resolution and thus the information content ... -
Development of a Bone Adhesive Material based on Diazirinyl-Collagen Mimetic Peptides
(2025-02-05)The treatment of small and inaccessible bone fractures with metallic implants is challenging. One potential solution to this issue is the use of an adhesive to adhere the affected fragments. In the search for new biocompatible ... -
Alpha-synuclein amyloid aggregation: From basic to translational research
(2025-02-05)Neurodegenerative diseases are a heterogeneous group of disorders affecting the lives of millions of people worldwide. A shared pathologic hallmark is the appearance of insoluble aggregates in the brain. The components of ... -
On the chemistry of sulfur: Development of NOS bridge model systems and Stereoretentive 2,3-bis(trifluoromethyl)cyclopropanation of heteroarenes via sulfonium salts
(2025-02-05)This thesis presents research conducted across two distinct projects in sulfur chemistry. The first project focused on the synthesis of model systems based on biphenyl, xanthene, and triazamacrocyclic scaffolds to investigate ... -
Single-cell studies of mammalian ovaries
(2025-01-31)Ovarian aging progresses more rapidly than in other organs. Female fertility declines exponentially after the age of 35, and as women increasingly delay childbearing, it is paramount to understand the underlying etiology ... -
Proteogenomic peptide discovery in large search spaces
(2025-01-30)Novel peptide and protein discovery is of therapeutical relevance and ignited the development of methods for their identification, commonly done via mass spectrometry. The latter relies on a well-characterised proteogenomic ... -
Enantioselective Synthesis and Postsynthetic Functionalization of Thiahelicenes and their Oxa-analogues
(2025-01-30)Based on the Alcarazo group’s experience in enantioselective Au(I)-catalyzed synthesis of (hetero)helicenes employing alkyne hydroaryration reactions, the gold precatalyst 188c, combining a chiral BINOL-derived backbone ... -
Quantitative Estimation of Cell Mechanical Cues using Elastic Micropillars
(2025-01-24)Within the intricate landscape of the cellular microenvironment, the inter- play between biochemical and physical signaling emerges as a decisive force shaping the physiology and functions of living cells. Recent insights ... -
Microbial Communities in the Terrestrial Subsurface
(2025-01-23)Terrestrial subsurface habitats represent a significant portion of Earth's prokaryotic biomass. However, our understanding of microbial diversity and functions in these environments, particularly in arid regions, remains ... -
Reductive Small Molecule Transformations with Pyrazolate-Based Bimetallic Complexes
(2025-01-23)The activation of small molecules (NO, O2, CO, CO2, N2, etc.) is important in a multitude of fields such as biology, medicine and industrial catalysis. Many synthetic catalysts were inspired by the active sites of ... -
Development of the detector readout for the ATLAS Phase II ITk pixel detector
(2025-01-23)During the HL-LHC upgrade, a high luminosity upgrade takes place, where the instantaneous luminosity will reach 7.5 × 10^(34) cm^(−2)s^(−1) in Run 4. The current inner detector of the ATLAS experiment will be replaced by ... -
Entwicklung eines integrierten Behandlungskonzeptes für die Kabatiella-Augenfleckenkrankheit (Kabatiella zeae) und die Turcicum-Blattdürre (Setosphaeria turcica) im Mais (Zea mays subsp. mays L.)
(2025-01-20)The aim of this study was to develop an integrated treatment concept for Northern corn leaf blight (Setosphaeria turcica) and Kabatiella eyespot (Kabatiella zeae) in maize (Zea mays subsp. mays L.) under Central European ... -
Middle-class consumers and alternative food networks in Bengaluru, India: Exploring pathways for transition to sustainable diets
(2025-01-17)The urgency for transitions toward sustainable food systems that promote and support sustainable diets is of critical importance for both planetary and human health and wellbeing. Currently, food systems are responsible ... -
Stochastic dynamics of driven Brownian particles in viscoelastic solvents
(2025-01-13)Since its seminal discovery by the botanist Robert Brown, Brownian motion has become an important paradigm in statistical physics. It describes the incessant, random motion of small (Brownian) particles suspended in a ... -
Genetic variation and inheritance of seed fiber components in oilseed rape (Brassica napus L.)
(2025-01-13)Oilseed rape (Brassica napus L.) is a major oil crop and a valuable protein source for animal and human nutrition. The oil-extracted meal of oilseed rape has a high protein content and a well-balanced amino acid composition. ... -
Higher Order Unfitted Space-Time Finite Element Methods for Moving Domain Problems
(2025-01-13)Finite Element methods are a well-established tool for simulating the behaviour of systems from various applications stemming from physics, engineering, and other sciences. In recent years, Unfitted Finite Element methods ... -
Electron Rich Metallo Nitrene Complexes For Nitrogen Transfer
(2025-01-10)The advent of C–N bond formation by catalytic C–H amination had a huge impact on the synthesis of nitrogen-containing compounds, in academia as well as industry. In contrast to nitrogen-group transfer, complementary ... -
Children’s Language Learning and Processing in Digital Social Interactions
(2025-01-10)Language is inherently a social tool, and nearly all questions concerning its origins, development, and processing raise a discussion of social interactions. As technological advancements transform how we communicate – ...