Blättern Zentren & Graduiertenschulen nach Betreuer & Gutachter "Alves, Frauke Prof. Dr."
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Preclinical evaluation of nanoparticle enhanced breast cancer diagnosis and radiation therapy
(2021-07-09)Triple negative breast cancer (TNBC) is an aggressive type of cancer which makes up 15-20% of all newly diagnosed cases, lacking the main target molecules for tumor specific treatment. Surgery or systemic therapy by ... -
NFATc1 driven ER-stress responses in the progression of non-alcoholic fatty liver disease
(2021-06-30)Non-alcoholic fatty liver disease (NAFLD) mirrors the hepatic manifestation of the metabolic syndrome and is defined by progressive fat accumulation in hepatocytes (steatosis). Uncomplicated NAFLD may progress to a severe ... -
Therapeutic approaches for two distinct CNS pathologies
(2020-06-19)This work summarizes the analysis of two distinct therapeutic approaches for the central nervous system (CNS) pathologies, Pelizaeus-Merzbacher disease (PMD) and Glioblastoma multiforme (GBM). PMD is a severe leukodystrophy ... -
Modulation of allergic airway inflammation by glucocorticoids
(2014-03-06)A crucial step in the development of improved drugs for asthma therapy is a thorough understanding of the mechanisms, which are important for effective treatment, and the identification of target cells in asthma pathogenesis. ...