• Multi-contrast Magnetic Resonance Imaging of Myelin and Iron in the Brain 

  Dadarwal, Rakshit (2022-09-27)

  The non-invasive characterization of brain myelin has essential applications in basic neuroscience and the clinical management of white matter brain diseases and other inflammatory and neurodegenerative diseases. Magnetic ...

• Simulation of fronto-parietal neural population activity to probe dimensionality reduction methods. 

  Filippow, Andrej (2022-09-20)

  Recent developments of optical and electrophysiological recording tools allow the detailed capture of large neuronal populations. Findings show that their activity is constrained to a low-dimensional manifold within the ...

• Actin promotes chromosome aggregation and accurate chromosome segregation in mammalian oocytes 

  Harasimov, Katarina (2022-09-15)

  Accurate chromosome segregation during meiosis is essential for the formation of a new life. During meiosis, spindle microtubules bind to the chromosomes’ kinetochores and arms in order to separate the genetic material. ...

• The Dynamic Organization of Proteins in the Synaptic Bouton 

  Reshetniak, Sofiia (2022-09-12)

  Protein availability is crucial for maintaining cellular processes. In synapses, the identities and functions of proteins involved in neurotransmission are well known. Their spatial distribution, copy numbers, and lifetimes ...

• The influence of epigenetic alterations on synaptic function and memory 

  Schroeder, Henning (2022-08-24)

  While memory formation is traditionally linked to changes in synaptic structure, the transcriptional processes enabling these changes are often understudied. Even though novel protein synthesis is the basis of long-term ...

• Adjustment of hydraulic, anatomical and leaf traits in Fagus sylvatica (L.) towards drier conditions. A study in mature stands. 

  Weithmann, Greta (2022-08-24)

  Hydraulic traits are closely linked to the ability of tree species to survive droughts and were therefore used to predict the disposition of trees to suffer from hydraulic failure in the face of climate change. While most ...

• Kinetic analysis of neuronal SNARE protein interactions 

  Pribićević, Sonja (2022-08-08)

  When an action potential arrives at the axon terminal, it causes a local and transient increase in the Ca2+ concentration that starts a cascade of molecular interactions eventually leading to the fusion of synaptic vesicles ...

• Neurovascular coupling in a central nervous system white matter tract 

  Restrepo Arango, Alejandro (2022-08-08)

  Neurovascular coupling is the process by which blood vessels dilate upon increased neuronal activity. It has been extensively studied in the murine grey matter and there are several models explaining possible molecular ...

• Molecular and circuit analysis of stable contrast processing in the visual system 

  Gür, Burak (2022-08-01)

  Visual perception gives us a reliable estimate of the world throughout the day, thanks to the computations implemented in visual circuits. In a given space or time, the relative change in luminance, contrast, forms the ...

• Intercellular Coordination in Epithelial Morphogenesis 

  Häring, Matthias (2022-07-26)

  During the development of an embryo, tissue rearrangements are driven by the precisely coordinated activity of thousands of cells. How this high degree of organization is achieved and regulated is one of the most important ...

• Modeling anti-NMDAR encephalitis 

  Wilke, Justus (2022-07-22)

  The anti-NMDAR encephalitis (NMDARE) is an autoimmune condition with so far unclear etiology and pathogenesis. It manifests with a heterogeneous clinical disease course and is diagnosed based on the presence of ...

• ¹⁷O hyperfine spectroscopy to investigate water binding to organic radicals 

  Hecker, Fabian (2022-07-22)

  Hyperfine spectroscopy experiments detect nuclear spins around paramagnetic centers. They reveal magnetic interactions that contain valuable structural information on distance and orientation of the coupling partners. One ...

• The confused flour beetle, Tribolium confusum A model for investigating Wolbachia-host interactions 

  Gharabigloozare, Yeganeh (2022-07-20)

  Summary Wolbachia, a group of maternally inherited intracellular endosymbiotic Alphaproteobacteria, are found in a wide range of arthropods and nematodes. It has been estimated that over 65% of insect species are infected ...

• Modifications in AP2 and clathrin-mediated endocytosis as a mechanism of synaptic plasticity 

  Sengül, Göksemin (2022-07-01)

  AP2 CME fulfills essential functions in embryonic development and cell survival. The AP2 complex and clathrin form AP2 CCV together with sixty other coat proteins. Due to this complex protein network, the regulation of CCV ...

• Understanding Nucleosome Assembly Regulation in Drosophila melanogaster 

  Mühlen, Dominik (2022-06-24)

  Nucleosomes consist of a complex of DNA and an octameric core of histone proteins, which represent the basic subunit of chromatin. The N-terminal tails of histones are target for chemical modifications, which play an ...

• From annotation to bacterial data models 

  Pedreira, Tiago (2022-06-24)

  Science and technological advancements walk side-by-side and with the recent emergence of novel high throughput techniques, the necessity to have specialized data structures to host and represent the complex and high variety ...

• Seasonal habitat use and breeding performance of the Eurasian Skylark (Alauda arvensis) in Central European farmland 

  Püttmanns, Manuel (2022-06-21)

  The Common Agricultural Policy (CAP) of the European Union has often been identified as a driver of recent agricultural intensification and thus of biodiversity loss. All major taxa, including vascular plants, arthropods, ...

• Regulation of vesicular trafficking in presence of mutations in contractile proteins 

  Dai, Yuanyuan (2022-06-20)

  The molecular and cellular mechanisms underlying disease phenotypes in dilated cardiomyopathy (DCM) are diverse and to date incompletely understood. Inherited mutations in genes encoding structural components of the sarcomere ...

• Characterization of immune responses in the meninges 

  Merlini, Arianna (2022-06-14)

  Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS), which is characterized by plaque-like demyelination in both white and grey matter and diffuse neurodegeneration. A T cell-driven ...

• Prospects for climate change mitigation of Scots pine and European beech forests 

  Förster, Agnes Julia (2022-06-03)

  The historic large-scale forest conversion in the northern German lowlands resulted in a man-made dominance of Scots pine, in a landscape that would naturally be dominated by forests of European beech. Since drawbacks of ...

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