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Untersuchung der pharmakologischen Modulation von ARNT-Homodimeren auf die Renoprotektion
(2023-10-02)Chronic kidney disease is marked by progressive fibrosis and consecutive loss of function – the availability of specific therapies is limited. The bHLH-PAS transcription factor ARNT is able to form homodimeric complexes ... -
Expression of gemcitabine metabolizing enzymes in different pancreatic cancer model systems
(2023-03-23)Pancreatic cancer still exhibits a dismal five-year overall survival rate of 9 % and is foreseen to even increase in incidence and mortality rates in the future. This is due to unspecific symptoms leading to late diagnosis, ... -
Vergleich der Lebersteifigkeit im rechten und linken Leberlappen, gemessen mittels 2D-Scherwellen-Elastographie (Gerät: LOGIQ E9, GE), bei Leber-gesunden Probanden sowie Patienten mit chronischer Lebererkrankung
(2021-06-23)The aim of this study was to compare liver stiffness measurement (LSM) values and the success rate of LSM in the right and left liver lobe, performed by 2D-shearwave elastography with the sonography device LOGIQ E9 (GE ... -
Malnutrition und Outcome bei älteren Patienten (≥ 65 Jahre) mit aggressiven Non-Hodgkin-Lymphomen
(2021-06-08)Both malnutrition and serum albumin (SA) have been shown to be independent negative predictors of impaired treatment response in many hematological malignancies. The body mass index (BMI) as an easily measurable value is ... -
Klinische Bedeutung des abführenden Schenkels im Vergleich zur Rektoskopie in der Diagnostik vor Ileostomarückverlagerung
(2020-07-23)In the context of visceral resections, the creation of an artificial bowel outlet (stoma) may be necessary. Among other aspects, the protective double loop ileostomy has become established. One lumen, which conveys the ...