Browsing Human- und Zahnmedizin by Advisor & Referee "Thoms, Sven Prof. Dr."
Now showing items 1-3 of 3
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Untersuchung von Translationalem Readthrough bei Peroxisomalen Biogenesestörungen im Zellmodell
(2025-05-19)Premature termination codon (PTC) mutations account for approximately 10% of pathogenic variants in monogenic diseases. Stimulation of translational readthrough, also known as stop codon suppression, using translational ... -
Calciumtransienten in Peroxisomen
(2024-11-12)Introduction: Peroxisomes are small cell organelles that play an important role in metabolic functions such as alpha- and beta-oxidation of fatty acids and ROS-homeostasis. So far the data of calcium concentrations and ... -
Biologische Mechanismen und pharmakologische Induzierbarkeit von translationalem Readthrough
(2021-12-06)Termination of translation is mediated when the A-site of the ribosome reaches a stop codon and release factors interact with the stop codon. Due to the competition between release factors and near-cognate tRNAs a stop ...