Browsing Human- und Zahnmedizin by Advisor "Haase, Detlef Prof. Dr."
Now showing items 1-4 of 4
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Genetische Varianten von PPM1D und TP53 bei Patienten mit myelodysplastischen Syndromen und komplex-aberranten Karyotypen
(2023-02-07)Myelodysplastic syndromes (MDS) are a heterogenous group of clonal bone marrow diseases leading to ineffective hematopoiesis. In over 90% cyto- and molecular genetic aberrations can be detected with complex aberrations ... -
Zusammenhänge zwischen TP53-Mutationsstatus, genetischer Instabilität und Prognose bei MDS und sekundärer AML mit komplex aberrantem Karyotyp
(2020-03-09)INTRODUCTION: In patients with MDS and secondary AML (sAML) complex aberrant karyotypes (≥ 3 clonal cytogenetic aberrations, CK) and mutations of TP53 are known to be prognostically adverse. There is evidence that TP53 ... -
Klonale Evolution und zytogenetische Evolutionsmuster bei Myelodysplastischen Syndromen (MDS) und sekundärer akuter myeloischer Leukämie nach MDS
(2016-03-10)Myelodysplastic syndromes (MDS) are clonal stem cell disorders characterized by heterogeneous symptoms and disease progression based on a multistep pathogenesis. Genetic instability promotes the gradual or sudden accumulation ... -
Progenitorzelleigenschaften bei myelodysplastischen Syndromen (MDS) mit Eisenüberladung
(2011-10-07)In patients with myelodysplastic syndromes (MDS) iron overload caused by long term red blood cell transfusions is an important factor for comorbity. In this report we present the results ...