Blättern Human- und Zahnmedizin nach "König, Sarah PD Dr." Betreuer
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Das Antihelminthikum Niclosamid inhibiert das Wachstum kolorektaler Karzinomzelllinien durch Modulation des kanonischen und des nicht-kanonischen Wnt-Signalweges
(2016-01-25)Wnt/ β-catenin-signalling is known to play an important role in colorectal cancer. Niclosamide, a salicylamide derivative used for the treatment of tapeworm infections, targets the Wnt/ β-catenin-pathway. The objective of ... -
In vivo Optical Imaging zum Nachweis der Leberrepopulation nach Konditionierung der Empfängerleber und Hepatozytentransplantation
(2014-05-23)Near infrared fluorescence (NIRF) optical imaging is a technique particularly powerful when studying in vivo processes at the molecular level in preclinical animal models. The purpose of this study was to assess optical ... -
Induktion und Reparatur von DNA-Doppelstrangbrüchen nach kombinierter Einwirkung von Cisplatin und Bestrahlung auf eukaryote Zellen
(2010-07-20)The efficacy of treatment with a combination of radiotherapy and chemotherapy in the yeast Saccharomyces cerevisiae as suitable eukaryotic model is demonstrated by following the induction ... -
Integration und Repopulation nach hepatozellulärer Transplantation im Rattenmodell
(2005-11-21)Initial clinical trials indicated promising results for hepatocyte transplantation as a clinically viable alternative to orthotopic liver transplantation in chronic liver disease. The ...