Browsing Human- und Zahnmedizin by Advisor "Kermer, Pawel Prof. Dr."
Now showing items 1-6 of 6
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Zur Rolle des Co-Chaperons BAG-1 im Glioblastoma-multiforme-Zellkulturmodell
(2016-07-15)Glioblastoma multiforme (GBM) is one of the most malignant brain neoplasias and the most common primary brain tumor in adults with a very poor prognosis. Many molecular pathologies have been found to account for GBM growth. ... -
Risikoprädiktion für sehr frühen Reinfarkt, Tod und Progression nach ischämischem Schlaganfall
(2013-12-20)Background: Early recurrent strokes lead to extended hospitalization and high number of complications. We investigated three stroke scores, the Essen Stroke Risk Score, the ABCD² and the Recurrence Risk Estimator for their ... -
Entwicklung und Evaluation eines neuen Modells für Synucleinopathien
(2013-11-19)Missfolding and oligomerization of alpha-synuclein is considered a central event in different neurodegenerative diseases like Parkinson’s disease and related disorders. As the function of alpha-synuclein is still a matter ... -
Die Funktion des BAG1-Proteins ist abhängig von seiner subzellulären Verteilung
(2011-04-07)BAG1 is a potent neuroprotectant as well as a marker of differentiation in neuronal cells. It is known that BAG1 mainly localises to the nucleus during neuronal development, whereas BAG1 ... -
BAG1 stellt die Bildung funktionaler DJ-1-L166P-Dimere und deren Chaperon-Aktivität wieder her
(2011-01-18)DJ-1 (PARK7) is the encoded protein from one of the four chromosomal loci associated with autosomal recessive, early onset parkinsonism. While evidence from genetic and biochemical studies ... -
Neuroprotektion durch BAG1 in Modellen des idiopathischen Parkinson-Syndroms
(2010-12-16)This work focuses on the different neuroprotective properties of the co-chaperone BAG1 (Bcl-2-associated athanogene-1) in various models of Parkinson's disease. In a SH-SY5Y cell culture ...