Browsing Human- und Zahnmedizin by Advisor "Mansur, Ashham Prof. Dr."
Now showing items 1-6 of 6
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Einfluss genetischer Varianten der negativ-kostimulierenden T-Zell-Inhibitoren TIM-3 und LAG-3 auf das Outcome von Patienten mit Sepsis
(2024-03-04)Background: Each year, millions of people die from sepsis or its consequences. Sepsis is defined as a life-threatening condition based on a dysregulated immune response to an infection. Thus, investigating the complex ... -
Auswirkungen einer Variation im TREM-1-Gen auf die Mortalität bei septischen Patienten
(2024-02-12)Sepsis is a life-threatening organ dysfunction caused by a disturbed immune response of the organism to an infectious agent. Sepsis is one of the most common causes of death in intensive care units. Due to its epidemiology ... -
Einfluss von Adipositas auf den Krankheitsverlauf sowie die 28- und 90- Tage Mortalität von Patienten mit Sepsis und septischem Schock
(2023-06-16)Sepsis, septic shock, and obesity remain subjects of significant interest in medical research and science. These diseases have a substantial impact on daily medical practices worldwide. Sepsis, a life-threatening condition, ... -
Einfluss chronischer Erkrankungen auf den Verlauf der Sepsis
(2022-01-13)According to previous studies, the clinical course of sepsis could be affected by preexisting medical conditions, which are very common among patients with sepsis. This observational study aimed at investigating whether ... -
Einfluss genetischer Varianten aus dem CTLA-4-Gen auf den Krankheitsverlauf von Patienten mit Sepsis
(2021-08-19)BACKGROUND: The cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is co-inhibitory immune checkpoint protein on the surface of T-cells. It transmits an inhibitory signal in the process of T-cell mediated immune response ... -
Assoziation des regulierenden Polymorphismus rs11536889 im TLR4-Gen mit Organ-spezifischer Morbidität und Mortalität bei Patienten mit Sepsis
(2020-09-08)Abstract Background Toll-like receptor 4 (TLR4), a lipopolysaccharide (LPS) receptor complex signal-transducing molecule, plays a crucial role in sensing LPS from gram-negative bacteria. TLR4 signaling pathway activation ...