Blättern Human- und Zahnmedizin nach "Staiger, Jochen Prof. Dr." Betreuer
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GABA(b)-Rezeptor-vermittelte Modulation an Martinotti-Zellen im primär somatosensorischen (Barrel-)Kortex der Maus
(2022-03-31)Under physiological conditions the brain is subject to continuous remodelling processes. In this case exizitation und inhibitation - and especially their balance - are important factors. Neuronal plasticity makes the brain ... -
Nachweis der Expression metabotroper GABAB-Rezeptoren in GABAergen Interneuronen des somatosensorischen Kortex mittels Immunhistochemie
(2021-10-01)In the cerebral cortex, different groups of neurons can be distinguished based on their mode of action. On the one hand, there are the excitatory neurons, which make up the majority (70-80 %) of neurons. The remaining 20-30 ... -
Elektrophysiologische Charakterisierung von GABA-Rezeptor-vermittelter Inhibition an Martinotti-Zellen der Schicht 5 im Barrel-Kortex
(2020-12-10)Martinotti cells (MC) belong to the subgroup of somatostatin-expressing GABAergic interneurons. They are an important component of cortical circuits and are involved in both lateral inhibition and disinhibition of principal ... -
Schichtenspezifische Charakterisierung von Parvalbumin-exprimierenden Neuronen im primären somatosensorischen Kortex der Maus
(2020-07-06)The neurons of the primary somatosensory cortex of the mouse can be divided into inhibitory and excitatory populations. The group of inhibitory interneurons, which comprise about 15-20% of the neurons, release the ... -
Loss of BAF155 impairs neurogenesis in the developing olfactory system of mice
(2019-11-19)Neurogenesis is a core developmental process which comprises the maturation of neural stem cells to fully developed neurons. Former studies have provided evidence that in the neuronal development of the central nervous ... -
Elektrophysiologische Charakterisierung GABA-Rezeptoren vermittelter Inhibition an Martinotti-Zellen im somatosensorischen Kortex
(2018-01-17)The processing of tactile information in the somatosensory cortex is currently not well understood. However, it is assumed that inhibitory interneurons play a key role in this process. When GABAergic neurons do not function ... -
Neuroligin-4: Einfluss auf die synaptische Übertragung exzitatorischer Neurone der Schicht IV des Barrel-Kortex
(2013-11-19)Neuroligins (NL) are predominant postsynaptically localized transmembrane adhesion molecules that interact with the presynaptically localized protein neurexin. There are different NL-isoproteins (NL 1 – NL 4) that differ ...