Dokumente Human- und Zahnmedizin nach Gutachter "Bogeski, Ivan Prof Dr."
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Characterization Of Pirfenidone Effects In Human Cardiac Fibroblasts
(2024-04-08)Background Cardiac fibrosis is a major problem in heart diseases, but it is still lacking an effective therapy. The drug pirfenidone has shown several anti-fibrotic effects in animal models of heart diseases and is already ... -
Die Rolle von Nicastrin in der Pigmentierung
(2022-12-19)The regulation of melanocyte function in the context of pigmentation is a complex biological process involving several molecular signaling pathways whose specific role is largely unknown. Recently, it was shown that a ... -
Extrakorporale Photopherese mit UVC-behandelten Leukozyten im Vergleich zu 8-MOP/UVA-behandelten Leukozyten zur Therapie der akuten graft-versus-host disease im Mausmodell
(2022-02-28)Graft-versus-host disease (GvHD) is a complication after allogeneic hematopoietic stem cell transplantation and responsible for the high morbidity and mortality rate. Extracorporeal photopheresis (ECP) is a common second-line ... -
Einfluss der Rett-Syndrom-assoziierten MeCP2-Defizienz auf die DNA-Oxidation, strukturelle und inflammatorische Marker in zerebralem Gewebe
(2021-11-26)Rett-Syndrome is a disorder with impaired neuronal development, in which mutations in the MECP2 gene lead to severe motor and cognitive impairment. Part of a complex clinical appearance are a disturbed cardiorespiratory ... -
UVC als Alternative zur 8-MOP / UVA-Behandlung in der extrakorporalen Photopherese
(2020-02-07)Background Graft-versus host complications and other (auto-)immune diseases are successfully treated with Extracorporeal Photopheresis (ECP), a widely accepted cellular therapy. The international standard for the ex vivo ... -
Über den Einfluss einer verringerten BRAP-Expression auf die Entwicklung der Atherosklerose im ApoE-defizienten Mausmodell
(2019-02-22)Atherosclerosis is among the leading causes of death in most parts of the world. The aetiology of this wide-spread, multifactorial disease is not yet entirely understood. Identified conventional risk factors include smoking, ...