Browsing Human- und Zahnmedizin by Referee "Kauffmann, Philipp Prof. Dr. Dr."
Now showing items 1-15 of 15
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Funktionelle Charakterisierung des organischen-Kationen Protonen Antiporters (H+/OC) und der Kationentransporter MATE1, MATE2-K, OCT1, OCT2, OCT3 und PMAT
(2025-12-10)Approximately 30% of all endogenous substances, as well as many drugs and other biologically relevant molecules, are organic cations. A central aim of this work was to investigate how these positively charged molecules ... -
Vergleich der konventionellen mit einer videogestützten Patientenaufklärung für eine diagnostische Gastroskopie – eine prospektiv randomisierte Studie
(2025-09-18)Background: A survey conducted by the European Society of Gastrointestinal Endoscopy (ESGE) highlights significant variability in the provision of medical information across Europe. Furthermore, it has been demonstrated ... -
Axonale Schädigung und Makrophageninfiltration bei Entmarkungserkrankungen
(2025-07-14)Even though the etiology of multiple sclerosis (MS) has been of scientific interest for a long time, it still remains unclear what exactly causes the axonal damage leading to neurological dysfunction. Especially since ... -
Modulation der zytosolischen Redox-Balance durch aktivitätsinduzierte Ca2+-Signale in hippokampalen Neuronen der Maus
(2025-06-24)Intracellular Ca2+ signals are essential for the modulation of cellular activity and excitability but also represent critical components of cellular dysfunction and damage in various neurological disorders. The aim of this ... -
Mikro CT-, Histomorphometrische- und Immunhistologische Analyse 3D gedruckter PLLA/CaCO3- Scaffolds mit Zusatz von CaPO4 im Göttinger Minipig zur Entwicklung eines patientenspezifischen, resorbierbaren Knochenersatzmaterials
(2025-06-12)Introduction: One of the central challenges in oral and maxillofacial surgery is the reconstructive restoration of tissue defects following extensive tumor resections in the head and neck region. Microvascular free tissue ... -
Einfluss der differenzierten Präsentation multipler Wachstumsfaktoren in biomimetischen Multilayerbeschichtungen von Titanimplantaten auf die Angiogenese und Osteogenese
(2025-05-16)The aim of the present study was to test the simultaneous and sequential release of the growth factors rhVEGF165 and rhBMP2 from poly-L-lysine-heparin (PLL-Hep) and poly-L-lysine-heparin-collagen (PLL-Hep-Col) poly-electrolyte ... -
Varianten im Dihydropyrimidin-Dehydrogenase-Gen (DPYD) bei Patienten mit Rektumkarzinomen unter adjuvanter, 5-FU-haltiger Chemotherapie – eine monozentrische Analyse aus der GAST-05-Studie
(2025-04-29)In this monocentric posthoc study the impact of occult mutational DPYD status in patients with adenocarcinomas (stages ≥ II) of the upper rectum was investigated towards the occurrence of CTC-AEs (Common-Toxicity-Criteri ... -
TransValid-A-Studie zur präoperativen, 5-FU-basierten Chemo-/Radiotherapie bei Rektumkarzinomen: Machbarkeit, Durchführbarkeit und erste Ergebnisse
(2025-03-14)The single-arm, multicenter TransValid-A study (ClinTrials. gov: NCT03034473; funded by the German Research Foundation, DFG; GZ: LI 1727/3-1) examined under real-world conditions the feasibility and efficacy of 5-fluorouracil ... -
Untersuchung zur Auswirkung eines Mund-Nasen-Schutzes auf die Mundgesundheit
(2025-03-06)Abstract The aim of this single-center, randomized, exploratory and controlled cross-over observational study was to investigate the influence of cloth, medical and FFP2 masks on saliva parameters and the occurrence of ... -
Gastrointestinale Motilität und infektiologischer Verlauf bei kritisch kranken Patienten mit spontaner intrazerebraler parenchymatöser Blutung
(2024-11-05)This study aims to identify the risk factors for the development of inflammatory processes such as systemic inflammatory response syndrome and sepsis in patients with spontaneous intracerebral parenchymal hemorrhage and ... -
Modulation der T-Zell-Infiltration und der Aktivierung von Makrophagen/Mikroglia bei der EAE durch zellspezifische Deletion des Arylkohlenwasserstoffrezeptors (AhR)
(2024-08-26)To better understand the pathomechanisms underlying multiple sclerosis, the role of the Ah receptor (AhR) in immune cell recruitment to the CNS was investigated using the murine experimental autoimmune encephalomyelitis ... -
Rauchverhalten vor und nach Diagnose und Therapie bei Patient*innen mit oralem Plattenepithelkarzinom
(2024-08-12)Smoking is one of the main risk factors for the development of oral squamous cell carcinoma. Additionally, patients who maintain tobacco consumption after diagnosis and therapy exhibit an increased risk of recurrence, a ... -
Characterization of urine proteome pattern changes associated with early diabetic nephropathy: a proteomic approach
(2024-04-19)Type 2 diabetes mellitus has become the most common cause of kidney failure in Europe and the United States. In Germany, 8.7 million people live with type 2 diabetes, although an estimated two million more affected people ... -
Symmetrievergleiche bei Patienten mit Lippen-, Kiefer-, Gaumenspalten anhand von dreidimensionaler Stereophotometrie
(2023-10-23)Cleft lip and palate are one of the most common craniofacial malformations. Patients do not suffer just from the functional limitations of this disease, but also from aesthetic limitations and associated psychosocial ... -
Dreidimensionale Gegenüberstellung von Planungszielen und postoperativen Ergebnissen bei konventioneller und digitaler Planung von Umstellungsosteotomien
(2023-10-23)Pronounced jaw malpositions in adults require surgical treatment, typically involving an interdisciplinary approach between orthodontics and maxillofacial surgery. Preoperative planning is crucial, as it aids in achieving ...