Browsing Human- und Zahnmedizin by Referee "Kermer, Pawel Prof. Dr."
Now showing items 1-6 of 6
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Risikoprädiktion für sehr frühen Reinfarkt, Tod und Progression nach ischämischem Schlaganfall
(2013-12-20)Background: Early recurrent strokes lead to extended hospitalization and high number of complications. We investigated three stroke scores, the Essen Stroke Risk Score, the ABCD² and the Recurrence Risk Estimator for their ... -
Entwicklung und Evaluation eines neuen Modells für Synucleinopathien
(2013-11-19)Missfolding and oligomerization of alpha-synuclein is considered a central event in different neurodegenerative diseases like Parkinson’s disease and related disorders. As the function of alpha-synuclein is still a matter ... -
Funktionelle Charakterisierung einer neuen Proteininteraktion zwischen Parkin und BAG1
(2012-07-24)Through its function as an E3 ubiquitin ligase Parkin plays an important role for the development of early-onset Parkinson´s disease (PD). Decreased Parkin activity may also contribute to the neurodegeneration of dopaminerg ... -
Messungen des Einflusses von Pregabalin auf die intra- und interhemisphärische Inhibition im humanen Motorkortex mittels transkranieller Magnetstimulation
(2011-06-08)Summary: Purpose: To explore acute effects of pregabalin (PGB) on human motor cortex excitability with transcranial magnetic stimulation (TMS). Methods: PGB, 600 mg/day, was orally administered ... -
BAG1 stellt die Bildung funktionaler DJ-1-L166P-Dimere und deren Chaperon-Aktivität wieder her
(2011-01-18)DJ-1 (PARK7) is the encoded protein from one of the four chromosomal loci associated with autosomal recessive, early onset parkinsonism. While evidence from genetic and biochemical studies ... -
Neuroprotektion durch BAG1 in Modellen des idiopathischen Parkinson-Syndroms
(2010-12-16)This work focuses on the different neuroprotective properties of the co-chaperone BAG1 (Bcl-2-associated athanogene-1) in various models of Parkinson's disease. In a SH-SY5Y cell culture ...