Browsing Human- und Zahnmedizin by Referee "Toischer, Karl Prof. Dr."
Now showing items 1-4 of 4
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Kardiale Effekte der m6A-Methylierung auf micro-RNA-Bindung
(2022-09-12)Heart failure is a common syndrome and of huge medial relevance. Increased stress levels lead to an enlargement of cardiomyocytes and the heart becomes hypertrophic. This is accompanied by changes in gene expression and ... -
Die Rolle des Protein-Phosphatase-1-Inhibitor-1 in der β-adrenergen Signalkaskade kardialer Fibroblasten
(2019-03-26)Heart failure is among the most common internal diseases in industrialized nations and associated with a high mortality rate. The sympathetic nervous system and β-adrenergic signaling play a crucial role in the pathophysiology ... -
Über die potenziell kardioprotektive Rolle des Hitzeschockproteins A4
(2020-08-06)Background: The protein quality control (PQC) plays a crucial role in cellular homeostasis. Accumulation of misfolded proteins can lead to a loss of function of cardiomyocytes and thus can contribute to heart failure. A ... -
Zelluläre Elektrophysiologie und Calciumhomöostase an Kardiomyozyten aus induzierten pluripotenten Stammzellen von einem Patienten mit Fallot'scher Tetralogie
(2021-08-26)Introduction: Tetralogy of Fallot (TOF) is the most common congenital cyanotic heart defect and many patients with TOF proceed to suffer from arrhythmias (both atrial and ventricular). The aim of this thesis was to identify ...