Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Advisor "Bastians, Holger Prof. Dr."
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The role of Wnt signalling in the microtubule-mediated maintenance of chromosomal stability
(2024-07-05)Chromosomal instability (CIN) is a major hallmark of cancer and represents a driving force for tumourigenesis, tumour progression, and the development of therapy resistance. CIN can be subdivided into structural CIN ... -
Molecular mechanisms of replication stress-induced mitotic chromosome missegregation
(2022-12-09)Chromosomal instability (CIN), the process of the generation of structural and numerical changes in the karyotype, is a major hallmark of human cancer generating genetic variation, thereby driving tumor evolution and ... -
CEP72 represents a putative Oncogene that negatively regulates the mitotic Function of Brca1 and induces Chromosomal Instability
(2015-10-26)Proper progression through mitosis ensures the maintenance of whole chromosomal stability in a eukaryotic cell. Hence, failures during this tightly regulated process can lead to the perpetual mis-segregation of whole ...