Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Advisor "Bohne, Wolfgang Dr."
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Identifizierung und Charakterisierung der Dihydroorotat Dehydrogenase als Zielstruktur von 1-Hydroxyquinolonen in Toxoplasma gondii
(2014-01-06)1-Hydroxyquinolones were recently described as effective inhibitors of Toxoplasma gondii replication. These compounds (e.g. HDQ and compound B) were previously shown to inhibit the alternative NADH dehydrogenase (NADH2-I) ... -
Biochemical Characterization of <i>Toxoplasma gondii</i> Type II NADH Dehydrogenases - Physiological Impact on Mitochondrial Functions and Energy Metabolism
(2010-03-09)The single subunit mitochondrial type II NADH dehydrogenases (NDH2s) in apicomplexan parasites have been considered as potential drug targets due to the absence in mammalian cells. Toxoplasma ... -
Kompartementalisierung des Kohlenhydrat-Stoffwechsels in Toxoplasma gondii
(2006-12-11)Toxoplasma gondii is an obligate intracellular parasite and which is able to infect and replicate within nearly any eukaryotic, nucleated cell. In the intermediate host the parasite ...