Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Advisor "Eichele, Gregor Prof. Dr."
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Studying the regulation and development of circadian clock by systems biology approaches
(2020-09-24)System biology approaches, coupled with emerging omics tools, have been widely used and greatly accelerated biological and medical research and discovery. In this thesis, I will focus on applying those tools and technologies ... -
TIP60 acetylation of BMAL1 links positive and negative arms of the molecular circadian clock
(2019-12-11)Many physiological processes exhibit circadian rhythms driven by cellular clocks composed of interlinked activating and repressing elements. The far-reaching influence of the circadian organization is illustrated by the ... -
Investigation of Structure and Function of Esco1 and Esco2 Acetyltransferases
(2018-12-04)Cohesin is a protein complex, whose core subunits are assembled into a ring-like structure encircling the DNA. In this manner, cohesin traps DNA molecules and plays key roles in expression, repair, and segregation of ... -
Effect of acute phase cytokines on iron uptake in hepatocytes and differential localization of Lipocalin-2 and Transferrin receptors in rat hepatic and extra hepatic organs
(2014-08-28)Acute phase response (APR) is the systemic reaction to tissue injury and inflammation. It is clinically characterized by systemic symptoms such as fever, weakness, and anemia, somnolence loss of appetite and cytokines ... -
Genetic disruption of the master pacemaker in the suprachiasmatic nucleus sheds light on the hierarchical organization of the mammalian circadian timing system
(2011-11-30)Circadian timing systems evolved in most organisms to adapt to the daily alternation of light and dark and the accompanying changes of environmental parameters such as food availability and predator occurrence. Circadian ...