Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Advisor "Griesinger, Christian Prof. Dr."
Now showing items 1-4 of 4
-
Characterization of the Phosphomimetic Mutant Y39E of a-Synuclein
(2024-08-06)α-Synuclein (aSyn) has long been identified as a key factor in the pathogenesis of Parkinson's Disease (PD), with familial mutations in the SNCA gene contributing to the aberrant aggregation of aSyn. Its aggregation results ... -
Biophysical characterization and computational modeling of phase separation of immune adapter proteins
(2022-07-07)The processes of B cell activation and development are stimulated by antigen binding to the B cell receptor. Pre-signaling clusters are present in unstimulated, resting B cells and assemble by tripartite phase separation ... -
NMR Spectroscopic studies of calmodulin plasticity in calcium signalling
(2008-03-18)The present work focused both in structural and dynamic studies on the ubiquitous Ca2+ signaling protein calmodulin. Calmodulin has been extensively studied both for its biological importance in the regulation of its ... -
Structure and dynamics of the aggregation mechanism of the Parkinson´s disease-associated protein alpha-synuclein
(2006-09-18)In Parkinson s disease (PD), intracellular neuronal inclusions containing amyloid-like aggregates of the protein alpha-synuclein (aS) are deposited in the pigmented nuclei of the brainstem. ...