Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Advisor "Ramadori, Giuliano Prof. Dr. Dr. h.c."
Now showing items 1-11 of 11
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Effect of radiation on hepatic fat metabolism in rat and mouse: A role of radiation-induced TNF-α in the regulation of FAT/CD36
(2015-08-13)Radiotherapy is an important method to treat tumors. The positive effects of irradiation on tumoral tissue are thought to be due to the damage of the DNA of tumor cells and the damage of tumor vessels. Radiation as single ... -
Differential gene expression of chemokines in KRAS and BRAF mutated colorectal cell lines: Role of cytokines
(2013-06-07)Background: Worldwide, colorectal cancer is the third most common malignancy. The development of the colorectal cancer (CRC) is a multistep process that involves e.g. an accumulation of mutations in tumor-growth promoting ... -
Serum Lipocalin-2 (LCN-2) as a major acute phase protein under different pathological conditions in vivo and in vitro studies
(2012-02-28)Lipocalin-2 (LCN-2) is a pleiotropic 25-kDa secretory protein, currently used as a biomarker for renal injury and inflammation. Its serum level is increased under different pathological ... -
Comparison of expression pattern and localization of iron transport proteins in rat liver, brain and spleen during acute phase response:invivo and invitro studies
(2012-02-09)Acute phase is clinically characterized by homeostatic alterations such as somnolence, adinamia, fever, muscular weakness and leucocytosis. Dramatic changes in iron metabolism are observed ... -
UPSTREAM PATHWAYS REGULATING ERYTHROPOIETIN GENE EXPRESSION IN THE LIVER DURING ACUTE PHASE RESPONSE: A CENTRAL ROLE FOR IL-6.
(2010-08-18)The acute phase response is the systemic reaction of an organism to insults like infection, trauma, or burning and it represents the first line of defense of the body to tissue-damaging ... -
Modulation of Gene Expression of Iron Regulatory Proteins, Hemeoxygenase-1 and Lactoferrin, in Mice Liver and Muscle by Different Cytokines, In Two Models of Acute Phase Reaction.
(2010-05-07)Iron is indispensable to living organisms. Iron homeostasis is orchestrated both at the cellular and the systemic level, and liver plays a central role in the regulation of iron ... -
Vergleich der Genexpression im entzündlichen Kolonepithel und im kolorektalen Karzinom im Hinblick auf das erhöhte Tumorrisiko bei chronisch entzündlichen Darmerkrankungen
(2008-02-04)In this thesis, the alterations are investigated that are responsible for an increased tumour risk in colonic epithelium of humans with inflammatory bowel disease (IBD). To detect early ... -
Characterization of foetal hepatic cells during rat liver development
(2006-11-06)During embryonic development the embryonic/foetal liver is the site where hepatogenesis and hematopoiesis take place. Hepatoblasts have been partly characterized in several previous studies. ... -
Serial Analysis of Gene Expression of Rat Liver Regeneration by Oval Hepatic Stem Cells
(2005-03-18)The liver has the unique capability to regenerate by itself after an injury. Normally adult hepatocytes maintain a perfect balance between cell gain and cell loss and they have the ability ... -
Molecular mechanisms of the cytokine-dependent induction of the heme oxygenase-1 gene: in vivo and in vitro studies
(2004-09-27)Heme oxygenase 1 (HO-1) is the inducible enzyme which catalyzes the rate-limiting reaction of heme degradation yielding carbon monoxide (CO), divalent iron (Fe2+), and biliverdin. Due to a ... -
Glucocorticoid receptor signalling and the effect of interleukin 1 beta on glucocorticoid mediated gene expression in intestinal epithelial cell lines Caco-2 and IEC-6
(2000-11-23)Background and aims: It has been reported that epithelial cells are involved in the process of inflammatory bowel disease (IBD) producing proinflammatory cytokines and chemokines. ...