Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Advisor "Rehling, Peter Prof. Dr."
Now showing items 1-6 of 6
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Investigation of TOMM20 Interactome in Relation to Protein Quality Control and Translocation
(2024-11-11)The human mitochondria are home to a vast repertoire of approximately 1,500 proteins, most of which are synthesized within the cytosol and post-translationally translocated into the mitochondria. Amidst the intricate ... -
Structural and functional characterization of TIM22 complex in the inner mitochondrial membarne
(2024-08-16)Mitochondria have gained significant attention in disease models due to their crucial role in cellular energy production and metabolic activity. Understanding how mitochondria maintain their function and interact with other ... -
Investigating the Role of ROMO1 in Mitochondrial Protein Import and Inner Membrane Morphology
(2018-10-18)Mitochondria are vital organelles that perform fundamental functions such as ATP synthesis and iron-sulfur cluster formation. More than 99% of the mitochondrial proteome is imported by dedicated translocation machineries. ... -
Protein interactions along the presequence import pathway
(2014-05-09)In this thesis the mechanisms of protein transport by the translocase of the inner mitochondrial membrane (TIM23) was investigated. Purified presequence peptides containing a p-benzophenyalalanine were established as a ... -
Biogenesis of respiratory chain: Rcf1 and Rcf2 as a novel assembly factors
(2012-07-04)The mitochondrial respiratory chain consists of four membrane-embedded electron transport complexes (complexes I – IV) and the ATP synthesizing F1F0ATPase. Within the inner mitochondrial membrane these complexes assemble ... -
Analysis of the role of Mdm38 in respiratory chain biogenesis
(2011-07-25)The present work illuminates the role of the mitochondrial protein Mdm38 in the biogenesis of the respiratory chain of the yeast Saccharomyces cerevisiae. It is a homolog of the human LETM1, ...