Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Advisor "Sereda, Michael Werner Prof. Dr."
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Molecular role of PMP22 in CMT1A
(2021-07-02)Myelinating Schwann cells wrap around peripheral axons and allow fast neural transmission. Peripheral myelin protein of 22 kDa (PMP22) is a transmembrane protein strongly expressed in Schwann cells. Alterations in PMP22 ... -
Metabolic alterations in Charcot-Marie-Tooth disease type 1A
(2021-05-03)Axo-glia interaction extend beyond myelination itself. Glial cells support axons with metabolites and trophic factors. In numerous disease models, primary glial mutations result in the disturbance of normal nerve conduction. ... -
The Role of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase (CNP) in the Peripheral Nervous System
(2015-10-19)In the peripheral nervous system (PNS) Schwann cells (SC) engulf, insulate and support motor and sensory axons. Nonmyelinating SC are associated with axons smaller than 1 µm in diameter, whereas myelinating SC form a compact ... -
Der Einfluss von Neuregulin-1 auf Erkrankungen des peripheren Nervensystems
(2014-07-08)A duplication of the gene encoding the peripheral myelin protein 22kDa (PMP22) underlies the commonest inherited neuropathy, Charcot Marie Tooth disease 1A (CMT1A). Although demyelination is a characteristic disease feature, ...