Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Referee "Hörner, Michael Prof. Dr."
Now showing items 1-10 of 10
-
Olfactory neurogenesis during tissue maintenance and repair
(2018-06-12)During metamorphosis, the African clawed frog Xenopus laevis undergoes a fundamental transformation from a fully aquatic larva to a secondarily aquatic adult. This extensive habitat change requires major adaptations including ... -
Molecular mechanisms of acute axonal degeneration in the rat optic nerve
(2015-12-03)The development of neuroprotective treatments is urgently needed for neurodegenerative and neurotraumatic diseases. As axonal degeneration is a key initiating event in these diseases, it is pivotal to better understand and ... -
Calcium and cAMP homeostasis determine network organisation of respiratory pre-Bötzinger neurons in Mecp2 null mice in vitro.
(2013-07-03)Rett Syndrome (RS) is a neurodevelopmental disorder caused primarily by mutations in a Mecp2 gene on the X chromosome that encodes methyl-cytosine binding protein (MeCP2). MeCP2 acts as a transcriptional repressor and an ... -
Stoichiometric Biology of the Synapse
(2013-05-07)Synaptic transmission at chemical synapses relies on the fusion of neurotransmitter-loaded vesicles with the plasma membrane of the pre-synaptic terminal (exocytosis). The synaptic vesicle material is then retrieved from ... -
Profiling the inherent vulnerability of motor neuron subtypes
(2012-01-05)Motor neuron diseases (MNDs) are a heterogeneous group of disorders that result in selective degeneration of upper and/or lower motor neurons (MNs). The precise causes of most MNDs remain ... -
Modulation of Histone Deacetylases Attenuates the Pathogenesis of Alzheimer's disease
(2011-04-12)SummaryWe are yet to learn precisely how we learn. The molecular and physiological mechanisms that govern the process of cognition remain a mystery to scientific minds around the globe. ... -
Molecular Mechanisms of Serotonergic Signaling: Role in Neuronal Outgrowth and Receptor Oligomerization
(2010-12-21)Role of 5-HT7/G12 signaling in morpho- and synaptogenesis. The neurotransmitter serotonin (5-hydroxytryptamine or 5-HT) modulates different aspects of early neuronal differentiation, including ... -
Die Rolle von transformierenden Wachstumsfaktoren-beta (TGF-β) in der Entwicklung von Synapsen
(2007-08-07)The transforming growth factors-beta (TGF-β) constitute a super-family of proteins that fulfil various functions during development and differentiation of the nervous system. However, their ... -
Neuroligins Determine Synapse Maturation and Function
(2007-07-10)This project investigated the role of neuroligins in brainstem respiratory network of NL 1-3 and NL 2 conventional knockout mice. The deletion of all three neuroligin genes leaded to a ... -
Stimulus-secretion coupling in pancreatic β-cells of healthy and diabetic rats in tissue slice preparation
(2006-07-04)A primary event in the development of type 2 diabetes is a decrease in the capacity of pancreatic β-cells to secrete insulin in response to glucose stimulation. The Goto Kakizaki (GK) ...