Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Referee "Pöhlmann, Stefan Prof. Dr."
Now showing items 1-10 of 10
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Analysis of the Antiviral Restriction Factor Shiftless in the context of HIV-1 Programmed –1 Ribosomal Frameshifting
(2024-07-05)The human immunodeficiency virus 1 (HIV 1) is responsible for a major global health crisis, the acquired immunodeficiency syndrome (AIDS) pandemic. Retroviruses integrate their genetic material into the genome of host ... -
Analysis of the Cell Entry of Enveloped Viruses and Identification of Potential Intervention Strategies
(2022-05-19)Viruses are a continuous threat for the human population. They are causing tremendous damage to human health and economy. Not only zoonotic viruses, which jump from animals to humans, but also the spread of highly adapted ... -
The establishment of a recombinant system for Papiine alphaherpesvirus 2
(2022-05-10)Simplexviruses of primates are closely related neurotropic herpesviruses that establish lifelong latent infections. While neuropathogenic infections are uncommon in their respective natural hosts, zoonotic transmission of ... -
A system for production of pure Influenza A virus defective interfering particles (DIPs) and assessment of their antiviral activity
(2021-09-09)Influenza A virus (IAV) epidemics and pandemics constitute a major threat to human health.The ability of IAV to rapidly acquire mutations can render antivirals and vaccines ineffective andnovel antiviral strategies are ... -
Pathogenesis of orthopoxvirus (OPXV) infection in common CM and identification of immune correlates after vaccination with differently attenuated vaccines
(2018-04-10)After the successful eradication of smallpox, mass vaccination stopped and the herd immunity against orthopoxvirus (OPXV) infections has been waning. In the light of bioterrorism, the interest in the development of antiviral ... -
Regulation of Toxoplasma gondii bradyzoite differentiation in terminally differentiated skeletal muscle cells
(2017-11-28)Toxoplasma gondii is an intracellular protozoan parasite that infects warm-blooded animals including an estimated thirty percent of humans world-wide. In immunocompetent host, primary infection is usually asymptomatic but ... -
Modifying the common marmoset monkey (Callithrix jacchus) genome: transgenesis and targeted gene modification in vivo and in vitro
(2015-11-25)The most widely used animal model for biomedical research is the mouse. Yet, the physiological differences between mice and humans sometimes result in findings of questionable translational value. The common marmoset ... -
Feinkartierung humoraler Immunantworten von Makaken nach Immunisierung und/oder viraler Infektion mittels Peptid - Microarray
(2014-10-02)The aim of this study was to map humoral immune responses in rhesus macaques (RM) which had either been immunized and/or infected with different viruses. This was achieved by screening serum samples using peptide microarrays. ... -
Functional analysis of the MERS-coronavirus spike protein
(2014-08-04)Ten years after the outbreak of the Severe Acute Respiratory Syndrome Coronavirus, SARS-CoV, which caused the first pandemic of the 21st century, a novel betacoronavirus, Middle East Respiratory Syndrome Coronavirus, ... -
Bedeutung der ACE2-Spaltung durch Wirtszellproteasen für die SARS-Coronavirus-Infektion
(2014-07-29)The Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) is a highly pathogenic virus and its zoonotic entry into the human population represents a substantial health threat. The identification of host cell factors ...