Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Referee "Papantonis, Argyris Prof. Dr."
Now showing items 1-5 of 5
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Investigation into gene regulatory networks governing the development and maintenance of the planarian reproductive system
(2024-03-20)Regulation of gene expression is a fundamental mechanism allowing the existence of complex living systems. This regulation takes shape in the form of hierarchical gene regulatory networks (GRNs), culminating in the binding ... -
Computational analysis of transcriptional regulation and chromatin assembly
(2023-12-07)Primordial germ cells (PGCs), the precursors of gametes, are specified from post-implantation epiblast cells in response to bone morphogenetic protein (BMP) signaling at the onset of gastrulation in mouse. Followed by ... -
Understanding the role of the transcription factor MGA in primordial germ cell differentiation
(2023-06-20)One of the most crucial cell lineage decisions in mammalian embryos is the differentiation of a few pluripotent epiblast cells into primordial germ cells (PGCs). PGCs are unique for their ability to mature into either sperm ... -
Genotype-Phenotype Correlation in Noonan Syndrome – Focus on LZTR1 and its Substrates
(2023-05-30)Noonan syndrome (NS) is a multisystemic disorder that is known as one of the most common monogenetic diseases associated with early-onset congenital heart defects, such as hypertrophic cardiomyopathy (HCM). Infants diagnosed ... -
Exploring the roles of RNAPII in genome organization
(2022-12-16)The role of RNAPII in 3D genome organization has been heavily debated over the last two decades. Here, in situ Hi-C and Micro-C data were used to conclusively address this debate. I discovered that: 1) using cell population ...