Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Referee "Rodnina, Marina Prof. Dr."
Now showing items 1-6 of 6
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Macromolecules in Motion by High-resolution Cryo-EM
(2024-05-06)Protein synthesis, the translation of the genetic code into a defined sequence of amino acids, is a central, highly dynamic and regulated step in gene expression. The well-defined bacterial translation system enables to ... -
Insights into the regulation of RNA helicases by protein cofactors
(2019-02-12)RNA helicases comprise a large family of ubiquitously expressed enzymes that remodel RNA structures and RNA-protein complexes in an NTP-dependent manner. These proteins are essential regulators of every RNA-related process, ... -
Structure of the Pol II initation complex with TFIIH and core Mediator and mechanistic implications for transcription
(2018-03-13)The transcription of protein coding genes is a key step in the conversion of genomic information into the content of a cell’s proteome. In eukaryotes, this process is performed by the multi-subunit DNA-dependent RNA ... -
Function of Elongation Factor P in Translation
(2016-04-25)The ribosome translates the genetic information encoded in the mRNA into amino acid sequence of a peptide chain. The catalytic site of the ribosome where peptide bonds are made, the peptidyl transferase center, consists ... -
Analyzing the eukaryotic translation initiation apparatus and new approaches in affinity chromatography
(2015-10-19)Eukaryotic translation is a multistep process that utilizes 47 individual translation factor subunits. eIF3 is the largest and most complex translation factor, acting during initiation where it promotes assembly of the 43S ... -
Structural and functional studies on GTPases involved in eukaryal translation initiation
(2015-06-05)Translation, the process of mRNA-encoded protein biosynthesis, is one of the fundamental processes that are universally conserved in extant cellular life. In all its major stages, namely initiation, elongation, termination ...