Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Referee "Walter, Lutz Prof. Dr."
Now showing items 1-12 of 12
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Analysis of the Antiviral Restriction Factor Shiftless in the context of HIV-1 Programmed –1 Ribosomal Frameshifting
(2024-07-05)The human immunodeficiency virus 1 (HIV 1) is responsible for a major global health crisis, the acquired immunodeficiency syndrome (AIDS) pandemic. Retroviruses integrate their genetic material into the genome of host ... -
The establishment of a recombinant system for Papiine alphaherpesvirus 2
(2022-05-10)Simplexviruses of primates are closely related neurotropic herpesviruses that establish lifelong latent infections. While neuropathogenic infections are uncommon in their respective natural hosts, zoonotic transmission of ... -
Treatment of acute Graft-versus-Host Disease using inorganic-organic hybrid nanoparticles
(2019-12-04)Acute Graft-versus-Host Disease (aGvHD) is a severe complication of allogeneic hematopoietic stem cell transplantation, which is induced by donor T cells that become stimulated after recognizing recipient proteins as ... -
Modifying the common marmoset monkey (Callithrix jacchus) genome: transgenesis and targeted gene modification in vivo and in vitro
(2015-11-25)The most widely used animal model for biomedical research is the mouse. Yet, the physiological differences between mice and humans sometimes result in findings of questionable translational value. The common marmoset ... -
GlmY and GlmZ: a hierarchically acting cascade composed of two small RNAs
(2014-09-10)In Escherichia coli and other enterobacteria, the homologous small RNAs (sRNAs) GlmY and GlmZ act in a hierarchical manner to feedback control expression of key enzyme glucosamine-6-phosphate (GlcN6P) synthase GlmS. Enzyme ... -
Effect of acute phase cytokines on iron uptake in hepatocytes and differential localization of Lipocalin-2 and Transferrin receptors in rat hepatic and extra hepatic organs
(2014-08-28)Acute phase response (APR) is the systemic reaction to tissue injury and inflammation. It is clinically characterized by systemic symptoms such as fever, weakness, and anemia, somnolence loss of appetite and cytokines ... -
In situ and in vitro analysis of germ and stem cell marker-positive cells in the postnatal ovary of the common marmoset monkey (Callithrix jacchus)
(2014-07-25)Oogonia are the proliferating diploid germ cells within the female gonad giving rise to oocytes. Oocytes are the meiotic female germ cell stages. In humans, almost all oogonia enter meiosis between weeks 9 and 22 of prenatal ... -
Myokardinfarktregeneration unter Verwendung kardiovaskulärer Vorläuferzellen aus murinen und humanen pluripotenten Stammzellen
(2013-02-19)Stem cells hold a great promise in regenerative therapies for cardiovascular diseases. Heart regeneration with stem cells requires a delicate balance between the loss of donor cell pluripotency (so that teratoma formation ... -
Association of killer immunoglobulin-like receptor genes with viral loads in experimental SIV infection of rhesus macaques (Macaca mulatta)
(2013-01-09)Multiple epidemiological studies in human demonstrated associations between KIR/MHC class I gene combinations and HIV-1 disease progression, implicating important roles of KIR-expressing NK cells in defencing HIV. The ... -
Comparison of expression pattern and localization of iron transport proteins in rat liver, brain and spleen during acute phase response:invivo and invitro studies
(2012-02-09)Acute phase is clinically characterized by homeostatic alterations such as somnolence, adinamia, fever, muscular weakness and leucocytosis. Dramatic changes in iron metabolism are observed ... -
Cellular Prion Protein (PrPC): Identification and Characterization of Novel Interacting Partners
(2011-12-07)The cellular prion protein (PrPC) is highly conserved throughout the evolution of mammals. (What does this sentence mean? What do you mean by ``conserved´´? This protein was higly conserved ... -
Genetic and functional characterisation of killer cell immunoglobulin like receptors (KIR) of rhesus macaques (Macaca mulatta)
(2011-02-24)This PhD thesis reports the characterisation of the genetic diversity of killer cell immunoglobulin like receptors (KIR) as well as interactions between KIR and MHC class I molecules in the ...