Blättern Fakultät für Chemie (inkl. GAUSS) nach "Steinem, Claudia Prof. Dr." Betreuer
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Laterale Organisation von Shiga Toxin gebunden an Gb3-haltige Modellmembranen
(2009-07-15)The aim of this study was to elucidate lateral organization of bound STxB (Shiga Toxin, B-subunit) and the reorganization of lipids upon protein binding by means of high-resolution scanning ... -
Modulation of lateral membrane tension and SNARE-mediated single vesicle fusion on pore spanning membranes
(2017-09-25)Synaptic vesicle fusion is driven by soluble N-ethylmaleimide-sensitive- factor attachment receptors (SNAREs) but is also regulated by physical properties of the membrane like curvature and tension. Using artificial SNARE ... -
Phase separation of biomimetic membranes:
(2019-12-11)The bacterium enterohemorrhagic Escherichia coli (EHEC) is one of the main causes of food borne illness. The toxin of this bacteria is shiga toxin (STx) which inhibits the protein biosynthesis of cells. Approaching the ... -
Phospholipidmembranen auf mikroporösen Substraten: in situ Bildung elektrochemischer Gradienten
(2013-07-11)Electrochemical gradients are of utmost importance for cellular processes, such as the generation of action potentials or the production of ATP in mitochondria. They are established by membrane proteins, which consume ... -
Reconstitution of Connexin-43 in Artificial Membranes
(2022-04-01)Synthetic biology aims to engineer complex biological functions in an artificial way. A variety of molecular tools and techniques allow mimicking of processes of living systems in a synthetic way. In that context, the ... -
Solid Supported Model Membranes Containing Plant Glycolipids: A Tool to Study Interactions between Diatom Biomolecules and the Silicalemma in vitro
(2017-06-22)Silica biomineralization in diatoms is presumably controlled by a self-assembly of biomolecules inside membrane-enclosed silica deposition vesicles. The fine-patterned structure of the diatom’s cell wall is thereby determined ... -
Spezifität der Wechselwirkung von Collybistin 2 mit Phosphatidylinositolphosphaten: Einfluss der verschiedenen Proteindomänen
(2015-05-27)Collybistin, a brain-specific GEF, is required for gephyrin clustering at the postsynaptic membrane. This is important for the correct arrangement of GABAA and glycine receptors. Binding of collybistin to a membrane is ... -
Structure and Mechanics of Membrane-bound Vimentin Filaments and Networks under Strain
(2022-12-16)The shape and mechanical properties of eukaryotic cells are determined by the cytoskeleton, composed of actin filaments, microtubules and intermediate filaments (IFs). Among these, IFs are considered to be the main ... -
Untersuchung einzelner SNARE-vermittelter Membranfusionsereignisse auf planaren porenüberspannenden Membranen
(2015-10-20)Even though there are a number of different in vitro fusion assays to analyze neuronal SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) mediated fusion, still the essential features of the in ... -
Verknüpfung zwischen Plasmamembran und Zytoskelett
(2016-09-22)The dynamic linkage between the plasma membrane and the underlying cytoskeleton of the cell is fundamental for cellular processes like cell morphogenesis, cell motility and cell adhesion. Ezrin as a member of the ERM ... -
Das vollständige HIV-1 Tat Protein überquert Lipidmembranen? Einfluss des positiven Ladungsclusters und des N-terminalen Bereichs
(2011-10-10)HIV-1 Tat belongs to the accessory proteins of HIV and has regulatory functions during the transcription of the viral RNA. Tat is concentrated in the nucleus and nucleolus of infected cells. ...