Dokumente Fakultät für Mathematik und Informatik (inkl. GAUSS) nach Gutachter "Waack, Stephan Prof. Dr."
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Gene Prediction with a Hidden Markov Model
(2004-02-11)Annotation of the large and rapidly increasing amount of genomic sequence data requires computational tools for finding genes in DNA sequences. This thesis presents a computational method ... -
Generic Methods for Adaptive Management of Service Level Agreements in Cloud Computing
(2015-11-27)The adoption of cloud computing to build and deliver application services has been nothing less than phenomenal. Service oriented systems are being built using disparate sources composed of web services, replicable datastores, ... -
Graph based fusion of high-dimensional gene- and microRNA expression data
(2013-01-25)One of the main goals in cancer studies including high-throughput microRNA (miRNA) and mRNA data is to find and assess prognostic signatures capable of predicting clinical outcome. Both mRNA and miRNA expression changes ... -
Graph Partitioning for the Finite Element Method: Reducing Communication Volume with the Directed Sorted Heavy Edge Matching
(2019-05-07)A technique called the Finite Element Method is primarily utilized to numerically solve Partial Differential Equations, most commonly by the use iterative methods, over a compact domain. The partial differential equations ... -
Graph-based Object Understanding
(2021-06-18)Computer Vision algorithms become increasingly prevalent in our everyday lives. Especially recognition systems are often employed to automatize certain tasks (i.e. quality control). In State-of-the-Art approaches global ... -
Improvement of the jpHMM approach to recombination detection in viral genomes and its application to HIV and HBV
(2011-08-08)Accurate virus genotyping and the detection of recombinant strains are of crucial importance for understanding viral evolution as well as the design of potential vaccines and treatment ... -
Increasing the robustness of active upper limb prostheses
(2017-02-02)This thesis is based on my work done at the Institute for Neurorehabilitation Systems at the University Medical Center Goettingen. My work has been partially founded by German Ministry for Education and Research (BMBF) via ... -
Information theoretical approaches for the identification of potentially cooperating transcription factors
(2019-08-08)Transcription factors (TFs) are a special class of proteins that usually bind regulatory DNA regions such as promoters and enhancers in order to control the expression of their target genes. Today, it is well known that ... -
Integration of Pathway Data as Prior Knowledge into Methods for Network Reconstruction
(2014-10-23)Hundreds of databases offer vast amounts of literature knowledge about biological signaling networks. However, this knowledge is rarely integrated into current bioinformatic analyzes due to challenges in the programmatic ... -
Interpretable Binary and Multiclass Prediction Models for Insolvencies and Credit Ratings
(2016-06-10)Insolvency prediction and credit rating are challenging tasks used to evaluate the creditworthiness of commercial enterprises based on qualitative and quantitative attributes. One way to approach these tasks is machine ... -
Learning Finite State Machine Specifications from Test Cases
(2010-08-05)Up-to-date software systems are often modular and need to be changeable. While modularity is believed to reduce software production costs, it also leads to increased difficulty in testing, ... -
Machine learning and statistical analysis to identify determinants of survival in primary glioblastoma using genome wide expression studies
(2022-07-05)Glioblastoma (GBM) is the most common and highly aggressive brain tumor. GBM poses unique challenges due to high rates of tumor recurrence ( 34%) and resistance to treatment. Despite advances in treatment strategies, the ... -
Mining Developer Dynamics for Agent-Based Simulation of Software Evolution
(2019-07-10)The steady growth of software in our daily life results in the need for quicker adaption of the software changing usage and requirements. This process is defined as software evolution. Primarily, it is concerned with changes ... -
Modellierung regulatorischer Netzwerke von Säugetieren und Einsatz von Methoden zur strukturellen Analyse und Identifikation von Kernkomponenten
(2011-06-21)Modeling and analysis of intracellular circuits with graph theoretical approaches has significantly improved the understanding of how regulatory systems are organized. However, only scarce ... -
Network Based Integration of Proteomic and Transcriptomic Data: Study of BCR and WNT11 Signaling Pathways in Cancer Cells
(2020-05-12)Bioinformatics applications in cancer research expanded rapidly over several years in the past. Due to the fast development of high throughput technologies, it became feasible to study the presence of hundreds of genes ... -
New approaches and software for sequence function prediction and gene design integrating specific knowledge on protein structure and translation
(2022-03-18)In recent years, advances in sequencing techniques resulted in an explosive increase in sequencing data. By now, there are billions of generated protein sequences available in public databases to a large extent without ... -
Obere und untere Schranken für eingeschränkte Parity-Branchingprogramme
(2006-08-15)Boolean Functions are classified in complexity classes by the upper and lower bounds of the resources a computation required to solve the function in a certain computation model.Thus one ... -
On Lower Bounds for Parity Branching Programs
(2003-12-18)This thesis concerns the complexity of parity branching programs with limitations on the way in which variables may be read.Interest in such branching programs has been raised by a popular ... -
On two Random Models in Data Analysis
(2017-03-02)In this thesis, we study two random models with various applications in data analysis. For our first model, we investigate subspaces spanned by biased random vectors. The underlying random model is motivated by applications ... -
PHOENIX: A Premise to Reinforce Heterogeneous and Evolving Internet Architectures with Exemplary Applications
(2020-12-02)The Internet was designed primarily for sharing expensive resources through establishing point-to-point connection using dedicated IP addresses. However, it has since evolved both in complexity and its number of users. ...