Browsing Fakultät für Physik (inkl. GAUSS) by Advisor "Köster, Sarah Prof. Dr."
Now showing items 1-10 of 10
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Investigation of Cells and Cellular Components with X-Rays in Liquid Sample Environments
(2024-08-07)Due to their short wavelength, X-rays offer a high spatial resolution and a high ability to penetrate soft condensed matter. Therefore, X-rays are well-suited for investigating structures and structural changes in in-vitro ... -
Interactions Within and Between Cytoskeletal Filaments
(2023-05-26)Cellular mechanics are determined by the cytoskeleton which consists of three different kind of biopolymers – actin filaments, microtubules and intermediate filaments – which form an intricate network. Each filament type ... -
Studying the Dynamics and Inhibition of Vimentin Assembly by Small-Angle X-ray Scattering
(2022-03-01)In this work, various methods are employed to investigate different aspects of the vimentin intermediate filament assembly process. Small-angle X-ray scattering provides insights on the occurring lateral assembly on the ... -
Low-dose, high-throughput scanning small-angle X-ray scattering of adherent mouse embryonic fibroblasts
(2022-02-24)Biological cells are highly variable: differences in e. g. gene expression emerge even among monoclonal cells in the same culture dish. The characterization of a highly variable statistical population calls for high-throughput ... -
Investigating cellular nanoscale with x-rays from proteins to networks
(2016-08-12)In this work, two macromolecules, both essential components of cells (keratin protein and DNA nucleic acid) were studied by X-ray techniques. I described the implementation and use of different methods to investigate these ... -
Mechanics of Intermediate Filaments
(2014-07-02)The eukariotic cytoskeleton consists of three major filament types: actin filaments, microtubules and intermediate filaments. While the first two filament types are highly conserved, intermediate filaments vary between ... -
Organization of the Cytoskeleton: Studies in Microfluidic Drops
(2014-05-19)The cytoskeleton is a cellular protein system, which acts as a scaffold for cells. The major fiber-forming constituents of the cytoskeleton are microtubules, actin filaments and intermediate filaments, which build networks ... -
Scanning X-Ray Nano-Diffraction on Eukaryotic Cells: From Freeze-Dried to Living Cells
(2013-12-13)The cytoskeleton of eukaryotic cells is a complex and dynamic network of different biopolymers, which plays an important role in, e.g., the determination of cellular shape, mechanical properties, and consequently specific ... -
Biophysics of Blood Platelet Contraction
(2013-05-21)This work is part of a project on blood platelet contraction using an innovative double approach to experiments. First, we adapted the experimental technique, traction force microscopy (TFM), to our cellular system, and ... -
Cation induced self-assembly of intermediate filaments
(2013-05-15)Cellular shape and the internal structure of living cells are defined by a dense network of three independent filament systems (actins, microtubules and intermediate filaments) termed "the cytoskeleton". Of these three ...